MMP-1 Inhibitor

MMP-1 Inhibitors (27):

Cat. No.	Product Name	Effect	Purity

HY-15768

Ilomastat	Inhibitor	98.33%
Ilomastat (GM6001) is a potent and broad spectrum matrix metalloprotease (MMP) inhibitor, inhibits MMPs (IC₅₀s, 1.5 nM for MMP-1; 1.1 nM for MMP-2; 1.9 nM for MMP-3; 0.5 nM for MMP-9), with a K_i of 0.4 nM for human skin fibroblast collagenase (MMP-1).

HY-N0262

Cordycepin	Inhibitor	≥99.0%
Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner.

HY-12169

Marimastat	Inhibitor	≥98.0%
Marimastat (BB2516) is a broad spectrum and orally bioavailable inhibitor of MMPs, with potent activity against MMP-9 (IC₅₀=3 nM), MMP-1 (IC₅₀=5 nM), MMP-2 (IC₅₀=6 nM), MMP-14 (IC₅₀=9 nM) and MMP-7 (IC₅₀=13 nM), used in the treatment of cancer.

HY-N1463

Luteolin 7-O-glucuronide	Inhibitor	99.80%
Luteolin 7-O-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC₅₀s of 17.63, 7.99, 11.42, 12.85, 0.03 μM for MMP-1, MMP-3, MMP-8, MMP-9, MMP-13, respectively.

HY-103444

ARP-100	Inhibitor	≥99.0%
ARP-100 is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC₅₀=12 nM).

HY-130076

MMP-2 Inhibitor II	Inhibitor
MMP-2 Inhibitor II (compound 2) is a selective MMP-2 inhibitor.

HY-114785

BPHA	Inhibitor
BPHA is a potent and orally active MMP-2, MMP-9 and MMP-14 inhibitor with IC₅₀s of 12 nM, 16 nM and 17 nM, respectively.

HY-N4028

Hydrangenol	Inhibitor
Hydrangenol is an orally active antiphotoaging compound.

HY-12170A

Prinomastat hydrochloride	Inhibitor	≥98.0%
Prinomastat hydrochloride (AG3340 hydrochloride) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC₅₀s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively.

HY-107394

UK 356618	Inhibitor	98.91%
UK 356618 (Compound 4j) is a potent and selective inhibitor of matrix metalloprotease-3 (MMP-3) with an IC₅₀ of 5.9 nM.

HY-12170

Prinomastat	Inhibitor	≥98.0%
Prinomastat (AG3340) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC₅₀s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively.

HY-107428

PD-166793	Inhibitor	≥99.0%
PD-166793 is a potent, selective, orally active and wide‐broad spectrum inhibitor of MMP, exhibiting nanomolar potency against MMP-2, MMP-3 and MMP-13 (IC₅₀=4, 7, and 8 nM, respectively) and micromolar potency vs MMP-1, -7 and -9 (IC₅₀=6.0, 7.2, and 7.9 μM, respectively).

HY-19485

XL-784	Inhibitor	98.13%
XL-784 is a selective matrix metalloproteinases (MMP) inhibitor, with IC₅₀s of ~1900, 0.81, 120, 10.8, 18, 0.56 nM for MMP-1，MMP-2，MMP-3，MMP-8，MMP-9，MMP-13，respectively.

HY-19677

Cipemastat	Inhibitor	99.81%
Cipemastat is a potent, competitive inhibitor of human collagenases 1, 2 and 3 with K_is of 3.0, 4.4 and 3.4 nM, respectively.

HY-114418

MMP3 inhibitor 1	Inhibitor	98.83%
MMP3 inhibitor 1 is a potent and highly selective MMP-3 inhibitor with an IC₅₀ of 1 nM.

HY-120793

CMC2.24	Inhibitor
CMC2.24 (TRB-N0224), an orally active tricarbonylmethane agent, is effective against pancreatic tumor in mice by inhibiting Ras activation and its downstream effector ERK1/2 pathway.

HY-117970

MMPI-1154	Inhibitor	99.87%
MMPI-1154 is a promising novel cardio-cytoprotective imidazole-carboxylic acid (ICA) MMP-2 inhibitor(IC₅₀=6.6 μM) and can be used for the study of acute myocardial infarction.

HY-W011085

CP-471474	Inhibitor
CP-471474 is an orally active and pan MMP inhibitor, with IC₅₀ values of 1170 nM (MMP-1), 0.7 nM (MMP-2), 16 nM (MMP-3), 13 nM (MMP-9) and 0.9 nM (MMP-13), respectively.

HY-146218

MMP-9-IN-5	Inhibitor
MMP-9-IN-5 is a MMP-9 inhibitor (IC₅₀: 4.49 nM) that forms hydrogen bond with MMP-9.

HY-107013

CP-544439	Inhibitor
CP-544439 is a potent and orally active matrix metalloproteinase-13 (MMP-13) inhibitor with an IC₅₀ of 0.75 nM.

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