Prostaglandin Receptor
Prostaglandin receptor, a sub-family of cell surface seven-transmembrane receptors, are the G-protein-coupled receptors. There are currently ten known prostaglandin receptors on various cell types. Prostaglandins bind to a subfamily of cell surface seven-transmembrane receptors, G-protein-coupled receptors. These receptors are named: DP1-2-DP1, DP2 receptors, EP1-4-EP1, EP2, EP3, EP4 receptors, FP-FP, IP1-2-IP1, IP2 receptors, TP-TP receptor. The prostaglandins are a group of hormone-like lipid compounds that are derived enzymatically from fatty acids and have important functions in the animalbody. There are currently ten known prostaglandin receptors on various cell types.
Prostaglandin Receptor Isoform Specific Products
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Prostaglandin Receptor Inhibitors
(169)
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Prostaglandin Receptor Agonists
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Prostaglandin Receptor Antagonists
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Prostaglandin Receptor Activators
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Prostaglandin Receptor Modulators
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Prostaglandin Receptor Inducers
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Prostaglandin Receptor Degrader
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Prostaglandin Receptor Controls
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Prostaglandin Receptor Ligands
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Prostaglandin Receptor Related Products (766)
Related Products (766)
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Antibodies (2)
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Prostaglandin Receptor Isoform Comparison
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15-Deoxy-Δ12,14-prostaglandin A2
0 ImagesCat. No.: HY-118055CAS No.: 112839-31-3Synonyms: 15d-PGA215-Deoxy-Δ12,14-prostaglandin A2 is a synthetic analog of PGA2.
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PGDM
0 ImagesCat. No.: HY-117659CAS No.: 133161-96-3Synonyms: Prostaglandin D MetabolitePGDM (Prostaglandin D Metabolite) is the main urinary metabolite of Prostaglandin D2 and is prone to reversible cyclization. PGDM may serve as a biomarker for the endogenous production of PGD2 or be used to evaluate the severity of acute allergic reactions.
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Meteneprost
0 ImagesCat. No.: HY-106077CAS No.: 61263-35-2Synonyms: U 46785Meteneprost (U 46785) is a cervical dilator that stimulates uterine contractions and dilates the cervical canal.
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L 640035
0 ImagesCat. No.: HY-118488CAS No.: 77167-93-2L 640035 is athromboxaneantagonist.
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IP/EP4 receptor agonist-1
0 ImagesCat. No.: HY-189067IP/EP4 receptor agonist-1 is a PGI2 analog and also an IP/EP4 receptor agonist. IP/EP4 receptor agonist-1 inhibits PAR-mediated integrin αIIbβ3 activation, P-selectin exposure, platelet aggregation and thrombus formation. IP/EP4 receptor agonist-1 can be used in research related to pulmonary hypertension.
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ST026567
0 ImagesCat. No.: HY-W511185CAS No.: 5067-25-4ST026567 is a potent mast cell activator. ST026567 induces the secretion of PGD2, LTC4 from cells. ST026567 exhibits degranulation potency.
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Pizuglanstat hydrate
0 ImagesCat. No.: HY-109134ACAS No.: 1584160-52-0Synonyms: TAS-205Pizuglanstat hydrate (Compound 3; TAS-205) is an orally active prostaglandin D synthase inhibitor with an IC50 of 76 nM for human hematopoietic prostaglandin D synthase. Pizuglanstat hydrate inhibits the synthesis of PGD2. Pizuglanstat hydrate improves experimental allergic rhinitis. Pizuglanstat hydrate can be used in the study of muscle regenerative diseases such as muscular dystrophy.
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17-trans Prostaglandin E3
0 ImagesCat. No.: HY-113481ACAS No.: 210979-33-217-trans Prostaglandin E3 is a prostaglandin analog, and stimulates Nurr1-dependent transcriptional activity. 17-trans Prostaglandin E3 can be used for research of condition associated with Nurr1,such as cancer and autoimmune disease.
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TASP0376377
0 ImagesCat. No.: HY-120867CAS No.: 1233246-60-0TASP0376377 is a potent and selective CRTH2 antagonist (IC50: 13 nM). TASP0376377 has binding affinity for CRTH2 (IC50: 19 nM).
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15(R)-15-Methyl Prostaglandin F2α
0 ImagesCat. No.: HY-139124CAS No.: 35864-81-4Synonyms: 15(R)-Carboprost; 15(R)-15-methyl PGF2α15(R)-15-Methyl Prostaglandin F2α (15(R)-Carboprost; 15(R)-15-methyl PGF2α) is a metabolically stable analog of PGF2α. 15(R)-15-Methyl Prostaglandin F2α is an inactive, prodrug PGF agonist designed for activation by gastric acid after oral administration. Acid-catalyzed epimerization of 15(R)-15-Methyl Prostaglandin F2α converts it into the active 15(S)-isomer. The 15(S)-isomer induces luteolysis when injected in rhesus monkeys at a dose of about 12 mg/animal, while the 15(R)-isomer does not.
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Latanoprost (Standard)
0 ImagesSynonyms: PHXA41 (Standard)Latanoprost (Standard) is the analytical standard of Latanoprost. This product is intended for research and analytical applications. Latanoprost (PHXA41) is a prostaglandin F2α analogue and an agonist for the FP prostanoid receptor, and lowers intraocular-pressure (IOP).
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Vapiprost hydrochloride
0 ImagesCat. No.: HY-105120ACAS No.: 87248-13-3Synonyms: GR 32191 hydrochlorideVapiprost hydrochloride (GR 32191 hydrochloride) is a thromboxane A2 receptor antagonist. Vapiprost hydrochloride (GR 32191 hydrochloride) inhibits the aggregation and ATP release stimulated with U-46619, collagen or arachidonic acid (AA) at an IC50 of less than 2.1×10-8 M.
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LCB 2853 sodium
0 ImagesCat. No.: HY-101700ACAS No.: 141335-11-7LCB 2853 sodium is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist. LCB 2853 sodium exhibits anti-aggregant and anti-vasospastic effects. LCB 2853 sodium can be used for the research of cardiovascular disease, such as hypertension.
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15(R)-PTA2
0 ImagesCat. No.: HY-137227CAS No.: 71154-83-1Synonyms: 15(R)-Pinanethromboxane A215(R)-PTA2 (15(R)-Pinanethromboxane A2) is an antithrombotic agent that inhibits platelet aggregation. 15(R)-PTA2 inhibits stable prostaglandin endoperoxide analog-induced constriction of feline coronary arteries and stabilizes hepatic lysosomes. 15(R)-PTA2 also inhibits thromboxane synthase but has no effect on prostacyclin synthase.
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20-Ethyl prostaglandin E2
0 ImagesCat. No.: HY-118414CAS No.: 37492-24-320-Ethyl prostaglandin E2 (compound 62) is a PG analog that stimulates Nurr1-dependent transcriptional activity.
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(E/Z)-3-Hydroxylicochalcone A
0 ImagesCat. No.: HY-N12571ACAS No.: 1083200-74-1(E/Z)-3-Hydroxylicochalcone A (Compound 1) is a flavonoid found in licorice (Glycyrrhiza inflata and
Glycyrrhiza uralensis), with antioxidant and anti-inflammatory activity. (E/Z)-3-Hydroxylicochalcone A inhibits lipid peroxidation in rat liver microsomes. (E/Z)-3-Hydroxylicochalcone A inhibits LPS (HY-D1056)-induced ROS, NO, IL-6, and PGE2 production.
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JAK05
0 ImagesCat. No.: HY-170586JAK05 exhibits inhibitory activity against Helicobacter pylori, inhibits strains J63, J196 and J107 with MIC of 3-5 µg/mL. JAK05 exhibits binding affinity to H+/K+-ATPase, COX-1/2, TNF-α and PGE2, reveals antioxidant and anti-inflammatory activities. JAK05 exhibits anti-ulcer activity in rat ethanol-induced gastric ulcer models.
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Flunoprost
0 ImagesCat. No.: HY-106757CAS No.: 86348-98-3Flunoprost is a stabilized prostaglandin E analogue.
