ADC Antibodies
ADC antibodies act as the navigation system of ADC drugs and are primarily responsible for delivering payloads to target cells.
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ADC Antibodies Related Products (136)
Related Products (136)
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Anti-FLT3 Antibody (AGS62P)
0 ImagesCat. No.: HY-P990786Anti-FLT3 Antibody (AGS62P) is an ADC antibody targeting FLT3, and can be used for acute myelogenous leukemia.
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LY4101174 Antibody
0 ImagesCat. No.: HY-P991742Purity: 99.46%Synonyms: 15A7.5; ETx-22 Antibody
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Mirvetuximab (powder)
0 ImagesSynonyms: M9346A (powder)
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Mipasetamab
0 ImagesMipasetamab is an IgG1κ antibody targeting to AXL, a tyrosine kinase receptor and an TAM Receptor. Mipasetamab involves in synthesis of ADCT-601 (Mipasetamab uzoptirine), an AXL-targeted antibody-drug conjugate (ADC). ADCT-601 has anti-tumor activity.
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Lixarkitug
0 ImagesSynonyms: AZD9829 antibody; INT-020Lixarkitug (AZD9829 antibody; INT-020) is a humanized IgG1κ antibody targeting IL-3Ra/CD123. Lixarkitug can be conjugated with Samrotecan to form the intact ADC molecule lixarkitug samrotecan (AZD9829), which is used in studies of acute myeloid leukemia (AML). The isotype control corresponding to Lixarkitug is Human IgG1 kappa, Isotype Control (HY-P99001).
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Anti-HER3 Antibody (Ab562)
0 ImagesCat. No.: HY-P991505Purity: 99.63%Synonyms: AMT-562 antibody
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Briobacept
0 ImagesCat. No.: HY-P99487CAS No.: 869881-54-9Synonyms: BR 3FCBriobacept (BR 3FC) is a recombinant glucoprotein, consists of 2 molecules from the BLyS receptor (BR3)and a Fc domain of human IgG1. Briobacept selectively targets to BLyS (BAFF), induces B cells apoptosis. Briobacept can be used in studies of rheumatoid arthritis (RA).
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IMGN388 Antibody
0 ImagesCat. No.: HY-P991644Purity: 99.0%IMGN388 Antibody is an Integrin targeting humanized monoclonal antibody. IMGN388 Antibody can be used for synthesis ADCs.
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Disitamab (powder)
0 ImagesCat. No.: HY-P99854ACAS No.: 2185868-98-6Synonyms: RC48-0 (powder)Disitamab (RC48-0) (powder) is a humanized monoclonal antibody targeting HER2. Disitamab (powder) can be used in the synthesis of antibody-drug conjugates (ADCs), Disitamab vedotin (HY-P9985).
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MGTA-117 Antibody
0 ImagesCat. No.: HY-P991294Purity: 99.50%MGTA-117 is a humanized monoclonal antibody targeting CD117. MGTA-117 can be used for synthesis of antibody-drug conjugate (ADC), utilizing an amanitin payload. MGTA-117 has potent anti-tumor activity and increases survival in three acute myeloid leukemia (AML) xenograft hNSG mice models (Kasumi-1, AML PDX 1 and AML PDX 2). MGTA-117 enables hematopoietic stem cell transplantation (HSCT) preprocessing in AML, myelodysplasia with excess blasts (MDS-EB) and gene therapy.
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Anti-CA6 Antibody (huDS6)
0 ImagesCat. No.: HY-P991649Purity: 98.03%Synonyms: SAR566658 antibodyAnti-CA6 Antibody (huDS6) is a Mucin 1-associated sialoglycotope (CA6) targeting humanized monoclonal antibody. Anti-CA6 Antibody (huDS6) can be used for synthesis of ADCs.
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ZV05
0 ImagesCat. No.: HY-P992488Purity: ≥99.0%Synonyms: ZV0501 AntibodyZV05 (ZV0501 Antibody) is an anti-5T4 monoclonal antibody with an EC50 of 4.3 ng/mL against h5T4. ZV05 does not induce apoptosis or interfere with cell cycle progression. ZV05 accumulates specifically in 5T4-positive tumor xenografts. ZV05 can serve as the antibody component of antibody-active molecule conjugates (ADCs) to bind the 5T4 glycoprotein, thereby enabling targeted delivery of toxins. ZV05 is used in studies of 5T4-positive cancers, including triple-negative breast cancer.
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Rolditamig
0 ImagesCat. No.: HY-P992130CAS No.: 3038136-62-5Synonyms: TQB2102 AntibodyRolditamig (TQB2102 Antibody) is a recombinant humanized anti-human epidermal growth factor receptor 2 (HER2) antibody. Rolditamig can be conjugated with an enzyme-cleavable linker and a topoisomerase I inhibitor to form the ADC TQB2102. Rolditamig is applicable to research on solid tumors such as HER2-positive breast cancer.
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BAY-79-4620 Antibody
0 ImagesCat. No.: HY-P992322Purity: 99.9%BAY-79-4620 Antibody is a potent and selective CAIX antibody with a human CAIX Kd of 3.6 nM. BAY-79-4620 Antibody yields antibody-drug conjugate (ADC) through conjugating with Monomethyl auristatin E (HY-15162) via a self-immolative enzyme-cleavable linker. BAY-79-4620 Antibody can be used for the research of cervical carcinoma, non-small cell lung carcinoma, breast carcinoma, pancreatic carcinoma, gastric carcinoma, prostate carcinoma.
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Sutantatug
0 ImagesSynonyms: SYS6002 Antibody; CRB-701 AntibodySutantatug (SYS6002 Antibody) is a monoclonal antibody targeting Nectin-4, and serves as the antibody moiety of the ADC CRB-701. Sutantatug is applicable to the research of Nectin-4-positive solid tumors, urothelial carcinoma and cervical cancer. The corresponding isotype control for Sutantatug is Human IgG1 kappa, Isotype Control (HY-P99001).
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REGN2878
0 ImagesCat. No.: HY-P992449Synonyms: PRLR ADC antibodyREGN2878 (PRLR ADC antibody) is a monoclonal antibody targeting the prolactin receptor (PRLR) and can block prolactin‑mediated activation of PRLR. REGN2878 exhibits an equilibrium dissociation constant (KD) of 1.05 nM and an IC50 of 0.344 nM for human PRLR. REGN2878 can be rapidly internalized and degraded in lysosomes by PRLR‑positive tumor cells, showing antigen‑specific binding and targeted enrichment properties. REGN2878 derivatives can be used as an immunoPET agent for antigen‑specific imaging of PRLR‑related tumors, and can also serve as a component of ADCs to exert anti‑tumor activity in breast cancer xenograft models. REGN2878 can be used in the research of breast cancer and prostate cancer. Isotype Comparison HY-P99001.
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Inotuzumab (powder)
0 ImagesCat. No.: HY-P99264ACAS No.: 1660159-36-3Synonyms: Humanized Anti-CD22 Recombinant Antibody (powder)Inotuzumab (Humanized Anti-CD22 Recombinant Antibody) (powder) is a humanized IgG4κ antibody that targets human CD22. Inotuzumab (powder) can be linked to a toxic agent Ozogamicin as an antibody-drug conjugate (ADC), Inotuzumab ozogamicin (HY-P9959). Inotuzumab (powder) can be used for the research of acute lymphoblastic leukemia and non-Hodgkin lymphoma.
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15N-Labeled Trastuzumab
0 ImagesCat. No.: HY-P9907S15N-Labeled Trastuzumab is the 15N-labeled Trastuzumab (HY-P9907). Trastuzumab is a humanized IgG1 monoclonal antibody that selectively binds to HER2 with high affinity. Trastuzumab can be used for the research of HER2-positive metastatic breast cancer and gastric cancer.
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ZV0201 Antibody
0 ImagesCat. No.: HY-P991982ZV0201 Antibody (ZV02) is a monoclonal antibody inhibitor targeting Her2. ZV0201 Antibody can be used to synthesize the antibody-drug conjugate (ADC) ZV0201. ZV0201 Antibody can be used to research related to HER2-positive tumors.
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STI-8811 Antibody
0 ImagesCat. No.: HY-P991877STI-8811 Antibody is an anti-human BCMA antibody. STI-8811 Antibody can generate antibody drug conjugate (ADC) (STI-8811) with an auristatin derivative, Duostatin 5 (HY-145149). STI-8811 Antibody can be used for the study of multiple myeloma.
