1. Signaling Pathways
  2. Anti-infection
  3. Antibiotic

Antibiotic

Antibiotic

Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-122386
    Kirromycin
    Kirromycin (Mocimycin; Delvomycin) is an elongation factor Tu (EF-Tu) inhibitor targeting protein biosynthesis. As an antibiotic, Kirromycin exerts antibacterial activity against Gram-negative bacteria by acting on EF-Tu to interfere with the peptidyl transfer reaction. Kirromycin is applicable to studies on bacterial infections.
    Kirromycin
  • HY-126198
    Linogliride
    Linogliride (MCN-3935) is an antidiabetic agent. Linogliride (100 μM) does not affect insulin secretion in the absence of glucose, but has a significant insulinotropic effect in the presence of 5.5 mM glucose.
    Linogliride
  • HY-N14237
    Epoxyquinomicin A
    Epoxyquinomicin A is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin A exhibits inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida and Staphylococcus aureus with a MIC of 3-12.5 µg/mL. Epoxyquinomicin A exhibits cytotoxicity in cancer cell L1210, B16 and S180 with IC50 of 2-8 µg/mL. Epoxyquinomicin A exhibits anti-inflammatory effects against collagen-induced arthritis.
    Epoxyquinomicin A
  • HY-N14507
    Mycinamicin VII
    Mycinamicin VII is a macrolide antibiotic. Mycinamicin VII shows activity against Gram-positive bacteria.
    Mycinamicin VII
  • HY-121104A
    Bactobolin hydrochloride
    Bactobolin hydrochloride (Compound 1) is an antibiotic, which inhibits Escherichia coli, Salmonella, Shigella, Staphylococcus and Bacillus subtilis, with MICs of 0.3-6.25 μg/mL. Bactobolin hydrochloride exhibits antitumor efficacy against leukemia, with a LD50 value of 6.25-12.5 mg/kg.
    Bactobolin hydrochloride
  • HY-B1088R
    Clopidol (Standard)
    Clopidol (Standard) is the analytical standard of Clopidol. This product is intended for research and analytical applications. Clopidol (WR-61112) is an anticoccidial agent which is used as feed additive to control coccidiosis in chickens. Clopidol inhibits the sporulation of Eimeria tenella oocysts.
    Clopidol (Standard)
  • HY-B0330DR
    (R)-Ofloxacin (Standard)
    (R)-Ofloxacin (Standard) is the analytical standard of (R)-Ofloxacin (HY-B0330D). (R)-Ofloxacin is the dextrorotatory enantiomer of Ofloxacin (HY-B0125) and is an orally effective fluoroquinolone antibiotic. (R)-Ofloxacin can inhibit the activity of bacterial DNA topoisomerase II, interfere with bacterial DNA replication and repair, and exert a bactericidal effect. (R)-Ofloxacin has a broad-spectrum antibacterial activity and has inhibitory effects on both Gram-negative and Gram-positive bacteria.
    (R)-Ofloxacin (Standard)
  • HY-N14004
    Clavamycin F
    Clavamycin F is a clavam antibiotic.
    Clavamycin F
  • HY-N14955
    3-O-α-D-Forosaminyl-(+)-griseusin
    3-O-α-D-Forosaminyl-(+)-griseusin is a memberof naphthoquinone antibiotic. 3-O-α-D-Forosaminyl-(+)-griseusin is active against Gram-positive bacteria including methicillin-resistant strain of Staphylococcus aureus (MRSA).
    3-O-α-D-Forosaminyl-(+)-griseusin
  • HY-N9499R
    3-Methoxyflavone (Standard)
    3-Methoxyflavone (Standard) is the analytical standard of 3-Methoxyflavone. This product is intended for research and analytical applications. 3-Methoxyflavone is a flavonoid compound isolated from Artemisia incanescens with antiviral activity[1][2].
    3-Methoxyflavone (Standard)
  • HY-N14684
    Griseusin B
    Griseusin B is a quinone antibiotic. Griseusin B mainly has anti-Gram-positive bacterial activity.
    Griseusin B
  • HY-W441968
    L-threo-β-Hydroxyaspartic acid
    L-threo-β-Hydroxyaspartic acid is an amino acid antibiotic. L-threo-β-Hydroxyaspartic acid has the activity of inhibiting Bacillus subtilis, Xanthomonas oryzae, Mycobacterium phlei and Botrytis cinerea.
    L-threo-β-Hydroxyaspartic acid
  • HY-N5167
    Argimicin A
    Argimicin A is an antibiotic that can be isolated from Sphingomonas sp.. Argimicin A exhibits algicidal activity against toxic cyanobacteria, inhibits M. viridis and M. aeruginosa with IC50s of 12 ng/mL and 100 ng/mL.
    Argimicin A
  • HY-125419
    Amythiamicin B
    Amythiamicin B is a trisubstituted pyridine thiopeptide with antibiotic properties against Gram-positive bacteria and activity against Plasmodium falciparum.
    Amythiamicin B
  • HY-N14919
    Olivanic acid
    Olivanic acid is a β -lactam antibiotic. Olivanic acid has the effect of anti -Gram-positive bacteria and anti-Gram-negative bacteria. Olivanic acid inhibits β-lactamase.
    Olivanic acid
  • HY-B0395S
    Sitafloxacin-d4
    Sitafloxacin-d4 (DU6859a-d4) is deuterium labeled Sitafloxacin. Sitafloxacin (DU6859a) is a potent, orally active fluoroquinolone antibiotic. Sitafloxacin shows antichlamydial activity and antibacterial activities against a broad range of gram-positive and gram-negative bacteria, including anaerobic bacteria, as well as against atypical pathogens. Sitafloxacin can be used for the research of respiratory tract infection and urinary tract infection.
    Sitafloxacin-d<sub>4</sub>
  • HY-N14836
    Macquarimicin C
    Macquarimicin C is an antibiotic.
    Macquarimicin C
  • HY-138075
    Obafluorin
    99.9%
    Obafluorin is a β-lactone antibiotic. Obafluorin inhibits threonyl-tRNA synthetase (PfThrRS) with an IC50 of 4.3 nM. Obafluorin inhibits the aminoacylation activity of EcThrRS and ObaO. Obafluorin exhibits Fe3+-enhanced antibacterial activity. Obafluorin can be used in studies related to infections caused by bacterial and parasites such as Plasmodium.
    Obafluorin
  • HY-A0248C
    Polymyxin B2 Sulfate
    Polymyxin B2 Sulfate is a polypeptide antibiotic with particularly potent antibacterial activity against Gram-negative bacteria. Polymyxin B2 Sulfate kills bacteria by binding to lipopolysaccharide molecules on the bacterial cell membrane, disrupting membrane integrity and causing leakage of intracellular contents. Polymyxin B2 Sulfate is used in studies related to Pseudomonas aeruginosa infection and acute enteritis.
    Polymyxin B2 Sulfate
  • HY-137323
    Leucinostatin H
    Leucinostatin H is a polypeptide antibiotic discovered in Paecilomyces marquandii, characterized by a tertiary amine-oxide terminal group. Leucinostatin H exhibits inhibitory activity against Gram-positive bacteria, such as Bacillus subtilis, B. cereus, and Staphylococcus aureus (MIC 10-100 μg/mL). Leucinostatin H holds potential for research in anti-infective and plant disease control applications.
    Leucinostatin H

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