2. Signaling Pathways
  3. Anti-infection
  4. Antibiotic

Antibiotic

Antibiotic

Antibiotic

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Antibiotics are a class of secondary metabolites produced from microorganisms, animals or plants. Some of them exhibit anti-bacterial, anti-fungal, anthelmintic, anti-tumor or immunosuppressive activities with a wealth of structural classes such as β-lactams, macrolide and polyether. As major sources of antibiotics, streptomycetes, penicillium and marine organisms produce a wide variety of commercially important polyketide compounds including the well-known macrolide, polyene and polyether antibiotics with wide range of activities. Antibiotics such as penicillin, cephalosporin, streptomycin, and tetracycline can be used in the treatment of human and veterinary diseases. However, antibiotic resistance is also a growing threat to global public health.

Antibiotic Isoform Specific Products:

Antibiotic Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14397
    8"-Hydroxypactamycin
    8''-Hydroxypactamycin is an antibiotic found in Streptomyces SIPI-A-3-0121.
    8
  • HY-16349R
    Nimorazole (Standard)
    Nimorazole (Standard) is the analytical standard of Nimorazole. This product is intended for research and analytical applications. Nimorazole (K-1900), a 2-nitroimidazole, is a hypoxic cell-radiation sensitizer. Nimorazole has anti-infective and anti-protozoal against trichomoniasis. Nimorazole has the potential for head and neck cancer.
    Nimorazole (Standard)
  • HY-N14503
    Mycinamicin Ⅳ
    Monamycin IV is an ester peptide antibiotic. Monamycin IV has activity against Gram-positive bacteria.
    Mycinamicin Ⅳ
  • HY-N14003
    Clavamycin E
    Clavamycin E is a clavam antibiotic.
    Clavamycin E
  • HY-17025S1
    Rifabutin-d6
    Rifabutin-d6 (Ansamycin-d6) is deuterium labeled Rifabutin. Rifabutin (Ansamycin) is a semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits DNA-dependent RNA polymerase.
    Rifabutin-d<sub>6</sub>
  • HY-N8519
    Urdamycin B
    Urdamycin B is an antibiotic that effectively inhibits fungi and bacteria. Urdamycin B also exhibits anti-proliferative activity against mouse leukemia cells L1210. Urdamycin B can be obtained from the metabolic products of Streptomyces fradiae. Urdamycin B can be used for research on cancer as well as bacterial and fungal infections.
    Urdamycin B
  • HY-B0497S2
    Niclosamide-d3
    Niclosamide-d3 (BAY2353-d3) is deuterium labeled Niclosamide. Niclosamide (BAY2353) is an orally active antihelminthic agent used in parasitic infection research. Niclosamide is a STAT3 inhibitor with an IC50 of 0.25 μM in HeLa cells. Niclosamide has biological activities against cancer, inhibits DNA replication in Vero E6 cells.
    Niclosamide-d<sub>3</sub>
  • HY-B1190S2
    Cefadroxil-13C6
    Cefadroxil-13C6 (BL-S 578-13C6) is 13C labeled Cefadroxil (HY-B1190). Cefadroxil is an orally active broad-spectrum cephalosporin antibiotic. Cefadroxil inhibits bacterial cell wall synthesis and enhances the expression of glutamate transporter-1. Cefadroxil is dependent on the intestinal peptide transporter PepT1 for small intestinal absorption. Cefadroxil has inhibitory and bactericidal activity against a variety of Gram-positive and Gram-negative bacteria and has analgesic effects on neuropathic pain.
    Cefadroxil-<sup>13</sup>C<sub>6</sub>
  • HY-19071
    BK-218
    BK-218 is an orally active cephalosporin antibiotic that binds to penicillin-binding proteins (PBPs) and has a greater inhibitory effect than Cephalexin (HY-B0200) and Cefoxitin (HY-B1825). BK-218 has similar antibacterial activity to Cefamandole (HY-B1128) and can be used in the development of antibacterial drugs.
    BK-218
  • HY-167651
    TAN-1057C
    TAN-1057C is a potent antibiotic which exhibits antibacterial activity against Gram-negative and Gram-positive bacteria, including Methicillin (HY-121544)-resistant Staphylococcus aureus.
    TAN-1057C
  • HY-105165
    Nortopixantrone
    Nortopixantrone (BBR 3438 free base) is a 9-aza-anthrapyrazole-based antineoplastic antibiotic. Nortopixantrone plays an important role in cacner research.
    Nortopixantrone
  • HY-B0147BR
    Pefloxacin mesylate dihydrate (Standard)
    Pefloxacin (Pefloxacinium) mesylate dihydrate (Standard) is the analytical standard of Pefloxacin mesylate dihydrate (HY-B0147B). This product is intended for research and analytical applications. Pefloxacin (Pefloxacinium) mesylate dihydrate is a broad spectrum antibiotic. Pefloxacin mesylate dihydrate blocks DNA replication by inhibiting DNA gyrase. Pefloxacin mesylate dihydrate inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin mesylate dihydrate exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin mesylate dihydrate has anti-Plasmodium yoelii infection activity. Pefloxacin mesylate dihydrate increase UVA-induced edema and immunesuppression. Pefloxacin mesylate dihydrate can be used for infection studies.
    Pefloxacin mesylate dihydrate (Standard)
  • HY-N15025
    Hydroxynybomycin
    Hydroxynybomycin is an antibiotic with anti-Gram-negative bacteria.
    Hydroxynybomycin
  • HY-N14577
    Pyrrolomycin D
    Pyrrolomycins D is a member of the pyrrolomycin group of antibiotic found in the Actinosporangium sp.
    Pyrrolomycin D
  • HY-N14762
    Leucomycin V
    Leucomycin V is a macrolide antibiotic. Leucomycin V has strong anti-Gram-positive bacterial effect, and also has an effect on spirochetes, Rickettsium and Chlamydia.
    Leucomycin V
  • HY-135549R
    Fluxapyroxad (Standard)
    Fluxapyroxad (Standard) is the analytical standard of Fluxapyroxad. This product is intended for research and analytical applications. Fluxapyroxad is a synthetic broad-spectrum fungicide for the control of fungal diseases. It works by inhibiting succinate dehydrogenase in complex II of the mitochondrial respiratory chain, resulting in inhibition of spore germination, germ tubes and mycelia growth within the fungus target species.
    Fluxapyroxad (Standard)
  • HY-N14308
    Aspiculamycin
    Aspiculamycin, a cytosine nucleoside, is an antibiotic. Aspiculamycin has a broad spectrum of antibacterial activity.
    Aspiculamycin
  • HY-N14400
    1-Hydroxysulfurmycin B
    1-Hydroxysulfurmycin B is an anthracycline antibiotic. 1-Hydroxysulfurmycin B has anti-Gram-positive bacteria and anti-tumor cell activity.
    1-Hydroxysulfurmycin B
  • HY-129435
    Altromycin E
    Altromycin E is an antibiotic, that exhibits antibacterial against Streptococci and Staphylococci with MIC of 0.2-3.12 μg/mL. Altromycin E can be used in anti-tumor research.
    Altromycin E
  • HY-N14092
    Chuangxinmycin
    Chuangxinmycin is an antibiotic that can be isolated from Actinoplanes tsinanensis CPCC 200056. Chuangxinmycin exhibits both in vitro and in vivo antibacterial activities and can be utilized in infection research.
    Chuangxinmycin
Antibiotic Isoform Comparison

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