2. Anti-infection
  3. Antibiotic
    Bacterial
  4. Cefoxitin

Cefoxitin 

Cat. No.: HY-B1825 Purity: 99.77%
COA Handling Instructions

Cefoxitin, a β-lactam antibiotic, is a broad-spectrum, second-generation cephalosporin. Cefoxitin has a broad spectrum antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria.

For research use only. We do not sell to patients.

Cefoxitin Chemical Structure

Cefoxitin Chemical Structure

CAS No. : 35607-66-0

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 50 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 50 In-stock
Estimated Time of Arrival: December 31
Solid
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 3 publication(s) in Google Scholar

Other Forms of Cefoxitin:

Top Publications Citing Use of Products

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Cefoxitin, a β-lactam antibiotic, is a broad-spectrum, second-generation cephalosporin. Cefoxitin has a broad spectrum antibacterial activity which includes anaerobic as well as Gram-positive and Gram-negative aerobic bacteria[1][2].

IC50 & Target

β-lactam

 

In Vitro

Cefoxitin has good activity against Gram-positive bacteria. The MICs for several Gram-positive pathogens are in the range of 1-6 μg/mL[1].
Cefoxitin exhibits high efficacy killing B. burgdorferi at concentration of 1.25 µM/mL[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo

Cefoxitin (20 mg/kg; i.p.; daily; for 5 days) effectively kills B. burgdorferi in C3H/HeN mice model[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Four-week-old female C3H/HeN mice[3]
Dosage: 20 mg/kg
Administration: Intraperitoneal injection, daily, for five consecutive days
Result: Had shown high efficacy killing B. burgdorferi in vivo.
Clinical Trial
Molecular Weight

427.45

Appearance

Solid

Formula

C16H17N3O7S2
CAS No.
SMILES

O=C(C(N12)=C(COC(N)=O)CS[[email protected]]2([H])[[email protected]@](NC(CC3=CC=CS3)=O)(OC)C1=O)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (233.95 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3395 mL 11.6973 mL 23.3945 mL
5 mM 0.4679 mL 2.3395 mL 4.6789 mL
10 mM 0.2339 mL 1.1697 mL 2.3395 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (5.85 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (5.85 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (5.85 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Cefoxitin35607-66-0AntibioticBacterialantibacterialcephalosporinLymediseaseInhibitorinhibitorinhibit

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