1. Anti-infection
  2. Antibiotic
    Bacterial
  3. Cefoxitin

Cefoxitin 

Cat. No.: HY-B1825 Purity: >98.0%
Handling Instructions

Cefoxitin is a broad-spectrum, second-generation cephalosporin with antibacterial activity. Cefoxitin is effective against a wide variety of infections caused by gram-positive or gram-negative aerobes as well as by anaerobic bacteria.

For research use only. We do not sell to patients.

Cefoxitin Chemical Structure

Cefoxitin Chemical Structure

CAS No. : 35607-66-0

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 50 In-stock
Estimated Time of Arrival: December 31
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Cefoxitin is a broad-spectrum, second-generation cephalosporin with antibacterial activity. Cefoxitin is effective against a wide variety of infections caused by gram-positive or gram-negative aerobes as well as by anaerobic bacteria[1][2].

In Vitro

Cefoxitin has good activity against gram-positive bacteria. The MICs for several gram-positive pathogens are in the range of 1-6 μg/mL[1].
Cefoxitin has shown high efficacy killing B. burgdorferi at concentration of 1.25 µM/mL[3].

In Vivo

Cefoxitin (20 mg/kg; i.p.; daily; for 5 days) effectively kills B. burgdorferi in vivo C3H/HeN mouse model[3].

Animal Model: Four-week-old female C3H/HeN mice[3]
Dosage: 20 mg/kg
Administration: Intraperitoneal injection, daily, for five consecutive days
Result: Had shown high efficacy killing B. burgdorferi in vivo.
Molecular Weight

427.45

Formula

C₁₆H₁₇N₃O₇S₂

CAS No.

35607-66-0

SMILES

O=C(C(N12)=C(COC(N)=O)CS[[email protected]]2([H])[[email protected]@](NC(CC3=CC=CS3)=O)(OC)C1=O)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (233.95 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.3395 mL 11.6973 mL 23.3945 mL
5 mM 0.4679 mL 2.3395 mL 4.6789 mL
10 mM 0.2339 mL 1.1697 mL 2.3395 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

CefoxitinAntibioticBacterialantibacterialcephalosporinLymediseaseInhibitorinhibitorinhibit

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Cefoxitin
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HY-B1825
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