2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3823):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-D3388
    BI dihydrochloride
    BI dihydrochloride is a DFHBI (HY-110250) derivative for imaging of RNA in cells. BI dihydrochloride increases brightness and photostability of Broccoli aptamers in cells. BI dihydrochloride enables imaging of single Broccoli-tagged mRNAs in living cells. BI dihydrochloride exhibits peak excitation of 470 nm and peak fluorescence emission of 505 nm when bound to Broccoli.
    BI dihydrochloride
  • HY-P2269
    MAIT-203
    MAIT-203, a cyclopentyalanin-derived peptidomimetic, potently inhibits the interaction of adenomatous polyposis coli (APC) and Asef (RhoGEF4), but not APC-Sam68 or APC-striatin interactions. MAIT-203 binds APC-ARM with a Ki of 0.015 μM and a Kd of 0.036 μM. MAIT-203 significantly represses the migration and invasion of colorectal cancer cells.
    MAIT-203
  • HY-N17409
    Eupatobenzofuran
    Eupatobenzofuran is a dihydrobenzofuran derivative that can be found in the aerial part of Eupatorium cannabinum subsp. asiaticum. Eupatobenzofuran inhibits fMLP/CB-induced elastase release by human neutrophils with an IC50 value of 11.3 μM.
    Eupatobenzofuran
  • HY-160968
    4-Demethoxy-7,9-di-epi-daunorubicin
    4-Demethoxy-7,9-di-epi-daunorubicin, a derivative of Daunorubicin (HY-13062A), is an anthracycline antibiotics. 4-Demethoxy-7,9-di-epi-daunorubicin can bind to calf thymus DNA and forms a complex with the stacked DNA base pairs. 4-Demethoxy-7,9-di-epi-daunorubicin can inhibit prokaryotic nucleic acid polymerases, including E. coli DNA polymerase I and RNA polymerase. 4-Demethoxy-7,9-di-epi-daunorubicin can be used for researches of cancer and infection.
    4-Demethoxy-7,9-di-epi-daunorubicin
  • HY-N9249
    6-(4-Hydroxy-3-methylphenyl)-2-methylhept-2-en-4-one
    6-(4-Hydroxy-3-methylphenyl)-2-methylhept-2-en-4-one is a natural sesquiterpene.
    6-(4-Hydroxy-3-methylphenyl)-2-methylhept-2-en-4-one
  • HY-N2108R
    7-Ethylcamptothecin (Standard)
    7-Ethylcamptothecin (Standard) is the analytical standard of 7-Ethylcamptothecin (HY-N2108). This product is intended for research and analytical applications. 7-Ethylcamptothecin is a derivative of Camptothecin (HY-16560) and a key intermediate in the synthesis of SN-38 (HY-13704). 7-Ethylcamptothecin can be used in tumor-related research.
    7-Ethylcamptothecin (Standard)
  • HY-181467
    KC159
    KC159 is a Yoda1 analog, as well as an agonist of Piezo1 and Piezo2. KC159 can be used for cultured adipocyte production.
    KC159
  • HY-N17062
    16-β-O-Ethylneoquassin
    16-β-O-Ethylneoquassin is a natural diterpene.
    16-β-O-Ethylneoquassin
  • HY-N9899
    Giraldoid A
    Giraldoid A (compound 1) is a dicoumarinoid glycoside found in the bark and rhizome of Daphne giraldii Nitsche.Giraldoid A can be used for the research of rheumatoid arthritis.
    Giraldoid A
  • HY-N2160A
    (E)-6'''-Feruloylspinosin
    (E)-6'''-Feruloylspinosin (Compound 3) is a flavonoid found in the seeds of Ziziphus jujuba Mill var. spinosa. (E)-6'''-Feruloylspinosin is a rotatable isomer of 6'''-Feruloylspinosin (HY-N2160).
    (E)-6'''-Feruloylspinosin
  • HY-47821
    WAY-655978
    		98.0%
    WAY-655978 is an active molecule.
    WAY-655978
  • HY-W1040921
    AY-31574
    AY-31574 is a 3, 5-difluoro derivative and selective mucosal protectant. AY-31574 is equipotent with Ranitidine (HY-B0693) against gastric injury caused by stress.
    AY-31574
  • HY-118809
    J 2931
    J 2931 is an active compound.
    J 2931
  • HY-124145
    Metfendrazine
    Metfendrazine is an active compound.
    Metfendrazine
  • HY-47595
    WAY-621089
    		98.0%
    WAY-621089 is an active molecule for the study of amyloid diseases and synucleinopathies.
    WAY-621089
  • HY-N17051
    Bisacurone A
    Bisacurone A is a natural sesquiterpene.
    Bisacurone A
  • HY-N9946
    Sophoradin
    Sophoradin is an isoprenyl chalcone and component of Guang-Dou-Gen (Shan-Dou-Gen). Sophoradin can be found in the roots of Sophora subprostrata CHUN et T. CHEN (Leguminosae). Sophoradin can be used for the research of tumors.
    Sophoradin
  • HY-N16857
    Didendronbiline A
    Didendronbiline A is a natural phenolic compound.
    Didendronbiline A
  • HY-163078
    C2-Gal-Dox
    C2-Gal-Dox is a galactose conjugate with high cytotoxicity. C2-Gal-Dox inhibits the growth of a variety of cancer cells.
    C2-Gal-Dox
  • HY-P11620
    H-Asn-Pro-Glu-Tyr(PO3H2)-OH
    H-Asn-Pro-Glu-Tyr(PO3H2)-OH is a phosphorylated peptide derivative of the tetramine motif Asn-Pro-Glu-Tyr (NPEY), and is a substrate binding domain common to the insulin-like growth factor-I receptor (IGF-IR) and the insulin receptor (IR).
    H-Asn-Pro-Glu-Tyr(PO3H2)-OH