2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Fat Mass and Obesity-associated Protein (FTO)
  5. Fat Mass and Obesity-associated Protein (FTO) Inhibitor

Fat Mass and Obesity-associated Protein (FTO) Inhibitor

Fat Mass and Obesity-associated Protein (FTO) Inhibitors (4):

Cat. No. Product Name Effect Purity
  • HY-151106
    FTO-IN-8
    		Inhibitor 98.03%
    FTO-IN-8 (FTO-43) is a N6-methyladenosine demethylase (FTO) (fat mass- and obesity-associated protein) inhibitor with the IC50 value of 5.5 μM. FTO-IN-8 has anti-cancer cell proliferative activity.
  • HY-117275
    Meclofenamic acid
    		Inhibitor
    Meclofenamic acid (Meclofenamate) is a non-steroidal anti-inflammatory agent. Meclofenamic acid is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid is a non-selective gap-junction blocker. Meclofenamic acid inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively.
  • HY-117275A
    Meclofenamic acid sodium hydrate
    		Inhibitor
    Meclofenamic acid (Meclofenamate) sodium hydrate is a non-steroidal anti-inflammatory agent. Meclofenamic acid sodium hydrate is a highly selective FTO (fat mass and obesity-associated) enzyme inhibitor. Meclofenamic acid sodium hydrate competes with FTO binding for the m(6)A-containing nucleic acid. Meclofenamic acid sodium hydrate is a non-selective gap-junction blocker. Meclofenamic acid sodium hydrate inhibits hKv2.1 and hKv1.1, with IC50 values of 56.0 and 155.9 μM, respectively.
  • HY-101082
    N6,2′-O-Dimethyladenosine
    		Inhibitor
    N6,2′-O-Dimethyladenosine, a substrate of fat mass and obesity-associated gene (FTO), is a reversible modification widely occurred on varied RNA molecules. N6,2′-O-Dimethyladenosine can regulate obesity.