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  3. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10878):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-131630S
    O-Desmethylmetoprolol-d5
    O-Desmethylmetoprolol-d5 is the deuterium labeled O-Desmethylmetoprolol.
    O-Desmethylmetoprolol-d<sub>5</sub>
  • HY-132651S
    Dehydro Mefloquine-d5
    Dehydro Mefloquine-d5 is the deuterium labeled Dehydro Mefloquine.
    Dehydro Mefloquine-d<sub>5</sub>
  • HY-132681S
    (Rac)-Cinacalcet-d3 hydrochloride
    (Rac)-Cinacalcet-d3 (hydrochloride) is the deuterium labeled (Rac)-Cinacalcet hydrochloride.
    (Rac)-Cinacalcet-d<sub>3</sub> hydrochloride
  • HY-B0632S
    Diltiazem-d6
    Diltiazem-d6 is the deuterium labeled Diltiazem. Diltiazem is an orally active L-type Ca2+ channel blocker, with antihypertensive and antiarrhythmic effects. Diltiazem can be used for the research of cardiac arrhythmia, hypertension, and angina pectoris.
    Diltiazem-d<sub>6</sub>
  • HY-141745S
    2-(((4-Methyl-7-oxooctyl)oxy)carbonyl)benzoic acid-d4
    2-(((4-Methyl-7-oxooctyl)oxy)carbonyl)benzoic acid-d4 is the deuterium labeled 2-(((4-Methyl-7-oxooctyl)oxy)carbonyl)benzoic acid.
    2-(((4-Methyl-7-oxooctyl)oxy)carbonyl)benzoic acid-d<sub>4</sub>
  • HY-W099463S
    Methyl 4-(N-(butylcarbamoyl)sulfamoyl)benzoate-d9
    4-Carboxy tolbutamide methyl ester-d9 is the deuterium labeled 4-Carboxy tolbutamide methyl ester.
    Methyl 4-(N-(butylcarbamoyl)sulfamoyl)benzoate-d<sub>9</sub>
  • HY-W013150S
    Alpidem-d14
    Alpidem-d14 is the deuterium labeled Alpidem (HY-W013150). Alpidem, an anxiolytic agent, is an orally active and brain-penetrant GABAA receptor ligand, binds to α1β2γ2 subunit-containing GABAA receptors (IC50 of 17 nM) over α5β2γ2 subunit-containing GABAA receptors (IC50 of >10 μM). Alpidem modulates calcium-induced mitochondrial permeability transition, induces glutathione depletion and hepatocyte necrosis, potentiates TNF-α toxicity, inhibits marble-burying and locomotor activity, enhances stressed rodent feeding behavior, and exerts anticonvulsant effects. Alpidem can be used for the research of anxiety, anxiety disorders, and convulsions.
    Alpidem-d<sub>14</sub>
  • HY-127166S
    Colchiceine-d3
    Colchiceine-d3 is the deuterium labeled Colchiceine.
    Colchiceine-d<sub>3</sub>
  • HY-132800S
    7-Methyl-3-methyluric acid-d3
    7-Methyl-3-methyluric acid-d3 is the deuterium labeled 7-Methyl-3-methyluric acid.
    7-Methyl-3-methyluric acid-d<sub>3</sub>
  • HY-17395AS
    Terbinafine-d7
    99.9%
    Terbinafine-d7 is the deuterium labeled Terbinafine. Terbinafine (TDT 067) is an antifungal medication used to treat fungal infections. It is a potent non-competitive inhibitor of squalene epoxidase from Candida with a Ki of 30 nM. Terbinafine also antibacterial activity against certain Gram-positive and Gram-negative bacteria.
    Terbinafine-d<sub>7</sub>
  • HY-B0661CS
    (Rac)-Tamsulosin-d3 hydrochloride
    (Rac)-Tamsulosin-d3 (hydrochloride) is the deuterium labeled (Rac)-Tamsulosin hydrochloride.
    (Rac)-Tamsulosin-d<sub>3</sub> hydrochloride
  • HY-B0802AS
    Terbutaline-d9
    Terbutaline-d9 is the deuterium labeled Terbutaline.
    Terbutaline-d<sub>9</sub>
  • HY-B0310S
    Nizatidine-d3
    98.80%
    Nizatidine-d3 is the deuterium labeled Nizatidine. Nizatidine is a potent and orally active histamine H2 receptor antagonist, can be used for the research of stomach?and?intestines ulcers. Nizatidine works by decreasing the secretion of gastric?acid the stomach makes and prevent ulcers from coming back after they have healed in animal models.
    Nizatidine-d<sub>3</sub>
  • HY-135212S
    Hydroxy ipronidazole-d3
    99.89%
    Hydroxy ipronidazole-d3 is the deuterium labeled Hydroxy ipronidazole. Hydroxy ipronidazole (Ipronidazole-OH) is a metabolite of nitroimidazole antibiotics, such as ipronidazole (IPZ). Hydroxy ipronidazole may has similar mutagenic potential as the parent compound.
    Hydroxy ipronidazole-d<sub>3</sub>
  • HY-135111S
    4-Desmethoxy Omeprazole-d3
    4-Desmethoxy Omeprazole-d3 is the deuterium labeled 4-Desmethoxy Omeprazole. 4-Desmethoxy Omeprazole is the active metabolite of Omeprazole. Omeprazole, a proton pump inhibitor (PPI), is available for treatment of acid-related gastrointestinal disorders. Omeprazole shows competitive inhibition of CYP2C19 activity with a Kiof 2 to 6 μM. Omeprazole also inhibits growth of Gram-positive and Gram-negative bacteria.
    4-Desmethoxy Omeprazole-d<sub>3</sub>
  • HY-141726S
    rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d3
    rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d3 is the deuterium labeled rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid.
    rel-(αR,βR)-β-(2,4-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic acid-d<sub>3</sub>
  • HY-17495AS
    Carteolol-d9 hydrochloride
    Carteolol-d9 (hydrochloride) is the deuterium labeled Carteolol hydrochloride. Carteolol hydrochloride (OPC-1085 hydrochloride) is a non-selective beta blocker used to treat glaucoma.
    Carteolol-d<sub>9</sub> hydrochloride
  • HY-B0286S
    Chlorpheniramine-d6 maleate
    Chlorpheniramine-d6 (maleate) is the deuterium labeled Chlorpheniramine maleate.
    Chlorpheniramine-d<sub>6</sub> maleate
  • HY-W052508S
    Norquetiapine-d8
    Norquetiapine-d8 (N-Desalkylquetiapine-d8) is the deuterium labeled Norquetiapine.Norquetiapine ( N-Desalkylauetiapine), a metabolite of Quetiapine (HY-14544), is a selective HCN1 channel inhibitor, with an IC50 of 13.9 μM. Norquetiapine selectively inhibits noradrenaline reuptake, is a partial 5-HT1A (Ki = 45 nM) receptor agonist, and acts as an antagonist at presynapticα2 (Ki = 237 nM), 5-HT2C(Ki = 107 nM), and 5-HT7 (Ki = 76 nM) receptors. Norquetiapine blocks the human cardiac sodium channel Nav1.5 in a state-dependent manner. Norquetiapine shows partial anti-inflammatory effects in LPS (HY-D1056) injected C57BL/6 mice. Norquetiapine can be used for the study of depression and inflammation.
    Norquetiapine-d<sub>8</sub>
  • HY-136907S
    (S)-Verapamil-d3 (hydrochloride)
    (S)-(-)-Verapamil-d3 (hydrochloride) is the deuterium labeled (S)-(-)-Verapamil hydrochloride.
    (S)-Verapamil-d<sub>3</sub> (hydrochloride)