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Reference Standards
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Reference Standards Related Products (11772)
Related Products (11772)
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Luvixasertib hydrochloride (Standard)
0 ImagesCat. No.: HY-101340ARCAS No.: 1610677-37-6Synonyms: CFI-402257 hydrochloride (Standard)Luvixasertib (hydrochloride) (Standard) is the analytical standard of Luvixasertib (hydrochloride) (HY-101340A). This product is intended for research and analytical applications. CFI-402257 hydrochloride is a highly selective and orally bioavailable TTK/Mps1 inhibitor with an IC50 of 1.7 nM for TTK in vitro. CFI-402257 hydrochloride has anti-cancer activity. -
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Octahydrocurcumin (Standard)
0 ImagesSynonyms: Hexahydrobisdemethoxycurcumin (Standard)Octahydrocurcumin (Hexahydrobisdemethoxycurcumin) is a hydrogenated derivative of curcumin and a metabolite of curcumin. Octahydrocurcumin is an orally active anticancer and anti-inflammatory agent, and is the final hydrogenated metabolite of Curcumin (HY-N0005) in vivo. Octahydrocurcumin exerts its anti-tumor and anti-inflammatory effects by inducing the mitochondrial apoptosis pathway and inhibiting the TAK1-NF-κB-COX-2 pathway, respectively. -
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5-BDBD (Standard)
0 ImagesCat. No.: HY-101911RCAS No.: 768404-03-15-BDBD (Standard) is the analytical standard of 5-BDBD (HY-101911). This product is intended for research and analytical applications. 5-BDBD, a potent and selective P2X4 receptor antagonist, inhibits rP2X4R-mediated currents, with an IC50 of 0.75 μM. 5-BDBD completely blocks the basal and acute hyperalgesia induced by nitroglycerin (NTG). -
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Lomibuvir (Standard)
0 ImagesSynonyms: VX-222 (Standard)Lomibuvir (Standard) is the analytical standard of Lomibuvir. This product is intended for research and analytical applications. Lomibuvir (VX-222), a selective, non-nucleoside polymerase inhibitor, targets thumb pocket 2 of the HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo-initiated RNA synthesis. -
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Infigratinib (Standard)
0 ImagesSynonyms: BGJ-398 (Standard); NVP-BGJ398 (Standard)Infigratinib (Standard) is the analytical standard of Infigratinib. This product is intended for research and analytical applications. Infigratinib (BGJ-398; NVP-BGJ398) is a potent inhibitor of the FGFR family with IC50s of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4, respectively. -
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Telithromycin (Standard)
0 ImagesCat. No.: HY-A0062RCAS No.: 191114-48-4Synonyms: HMR3647 (Standard); RU66647 (Standard)Telithromycin (Standard) is the analytical standard of Telithromycin. This product is intended for research and analytical applications. Telithromycin (HMR3647) is a novel ketolide antibiotic that structurally resembles macrolides. Telithromycin belongs to the ketolide family that is characterized by a keto group at position 3 of the macrolide ring and is active against bacteria causing community-acquired pneumonia, acute exacerbation of chronic bronchitis, and acute sinusitis. Telithromycin also has similar immunomodulatory effects as macrolides. Telithromycin can be used for the research of respiratory infections including bronchial asthma. -
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Acebutolol hydrochloride (Standard)
0 ImagesAcebutolol (hydrochloride) (Standard) is the analytical standard of Acebutolol (hydrochloride). This product is intended for research and analytical applications. Acebutolol hydrochloride is an orally active β1 adrenergic receptor (β1AR) antagonist. Acebutolol hydrochloride is used in the treatment of hypertension, angina pectoris and cardiac arrhythmias. -
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Deserpidine (Standard)
0 ImagesCat. No.: HY-107339RCAS No.: 131-01-1Synonyms: Harmonyl (Standard)Deserpidine (Standard) is the analytical standard of Deserpidine. This product is intended for research and analytical applications. Deserpidine (Harmonyl) is an alkaloid isolated from the root of Rauwolfia canescens related to Reserpine. Deserpidine is used as an antihypertensive agent and a tranquilizer. Deserpidine is a competitive angiotensin converting enzyme (ACE) inhibitor. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex. -
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Cyphenothrin (Standard)
0 ImagesCat. No.: HY-119335RCAS No.: 39515-40-7Synonyms: S-2703 (Standard)Cyphenothrin (Standard) is the analytical standard of Cyphenothrin. This product is intended for research and analytical applications. Cyphenothrin (S-2703) is a pyrethroid pesticide. Cyphenothrin acts on the neuromuscular system of insects, intervening in the gating mechanism of sodium channels. -
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Propyl pyrazole triol (Standard)
0 ImagesCat. No.: HY-100689RCAS No.: 263717-53-9Synonyms: PPT (Standard)Propyl pyrazole triol (Standard) is the analytical standard of Propyl pyrazole triol. This product is intended for research and analytical applications. Propyl pyrazole triol (PPT) is a selective estrogen receptor alpha (ERα) agonist. The relative binding affinity of Propyl pyrazole triol for ERα (ERα: 49%) around 410 times higher compared with estrogen receptor beta (ERβ: 0.12%). -
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CGP 57380 (Standard)
0 ImagesCat. No.: HY-10520RCAS No.: 522629-08-9CGP 57380 (Standard) is the analytical standard of CGP 57380 (HY-10520). This product is intended for research and analytical applications. CGP 57380 is a cell-permeable pyrazolo-pyrimidine compound that acts as a selective inhibitor of Mnk1 with IC50 of 2.2 μM, but has no inhibitory activity against p38, JNK1, ERK1/2, PKC, or Src-like kinases. -
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MT-7716 hydrochloride (Standard)
0 ImagesCat. No.: HY-107094RCAS No.: 1215859-93-0Synonyms: W-212393 hydrochloride (Standard)MT-7716 hydrochloride (Standard) (W-212393 hydrochloride (Standard)) is the analytical standard of MT-7716 hydrochloride (HY-107094). This product is intended for research and analytical applications. MT-7716 hydrochloride (W-212393 hydrochloride) is a selective non-peptide nociceptin receptor (NOP) agonist and promising potential treatment drug for alcohol abuse and relapse prevention. -
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NSC49652 (Standard)
0 ImagesCat. No.: HY-111163RCAS No.: 908563-68-8NSC49652 (Standard) is the analytical standard of NSC49652 (HY-111163). This product is intended for research and analytical applications. NSC49652 is a reversible, orally active p75 neurotrophin receptor (p75NTR, also known as NGFR, TNFRSF16, and CD271) agonist. NSC49652 targets the transmembrane domain of p75NTR. NSC49652 induces apoptosis and affects the viability of melanoma cells. -
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Pentamidine (Standard)
0 ImagesPentamidine (Standard) is the analytical standard of Pentamidine. This product is intended for research and analytical applications. Pentamidine (MP-601205) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities. -
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2-(((4-chloro-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-6-methoxy-1Hbenzo[d]imidazole (Esomeprazole Impurity) (Standard)
0 ImagesCat. No.: HY-Z2146RCAS No.: 863029-89-42-(((4-chloro-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-6-methoxy-1Hbenzo[d]imidazole (Esomeprazole Impurity) (Standard) is the analytical standard of 2-(((4-chloro-3,5-dimethylpyridin-2-yl)methyl)sulfinyl)-6-methoxy-1Hbenzo[d]imidazole (Esomeprazole Impurity). This product is intended for research and analytical applications. -
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Metipranolol (Standard)
0 ImagesCat. No.: HY-121567RCAS No.: 22664-55-7Metipranolol (Standard) is the analytical standard of Metipranolol. This product is intended for research and analytical applications. Metipranolol is a nonselective and orally active β-adrenergic receptor antagonist. Metipranolol can be used for hypertension and glaucoma research. -
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MLN8054 (Standard)
0 ImagesCat. No.: HY-10180RCAS No.: 869363-13-3MLN8054 (Standard) is the analytical standard of MLN8054. This product is intended for research and analytical applications. MLN8054 is a potent, selective and orally available aurora A kinase inhibitor with an IC50 of 4 nM. -
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Dipropofol (Standard)
0 ImagesDipropofol (Standard) is the analytical standard of Dipropofol. This product is intended for research and analytical applications. Dipropofol is a dimeric derivative of Propofol (HY-B0649) with antioxidant and antibacterial activities. Dipropofol terminates free radical chain reactions, scavenges DPPH free radicals and inhibits lipid peroxidation. Dipropofol protects cells from death induced by glutamate, Aβ(25-35) and buthionine sulfoximine, and increases the survival rate of mice exposed to oxygen. Dipropofol selectively activates tonic GABAA currents, hyperpolarizes resting membrane potential, reduces action potential firing, and alleviates the severity of seizures induced by Kainic acid. Dipropofol can be used in the research of Gram-positive bacterial infections, Alzheimer's disease, cerebral ischemia-related neuronal injury, oxygen toxicity and temporal lobe epilepsy. -
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AM6545 (Standard)
0 ImagesCat. No.: HY-110206RCAS No.: 1245626-05-4AM6545 (Standard) is the analytical standard of AM6545 (HY-110206). This product is intended for research and analytical applications. AM6545 is a highly selective, brain-free (peripherally active) CB1 receptor antagonist (Ki=1.7 nM). AM6545 inhibits endocannabinoid signaling by competitively antagonizing CB1 receptors, inhibiting CB1-mediated appetite stimulation and inflammatory responses without affecting cAMP levels. AM6545 significantly reduces food intake and body weight in mice, while improving metabolic syndrome-related renal impairment (such as proteinuria, fibrosis) and insulin resistance. AM6545 can be used in the study of obesity and its complications. -
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1-Methyl-2-(methylthio)-1H-imidazole (Standard)
0 ImagesCat. No.: HY-N8848RCAS No.: 14486-52-3S-Methylmethimiazole (Standard) is the analytical standard of S-Methylmethimiazole. This product is intended for research and analytical applications. -
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