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Reference Standards
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Reference Standards Related Products (11046)
Related Products (11046)
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MNI137 (Standard)
0 ImagesCat. No.: HY-103572RCAS No.: 946619-21-2MNI137 (Standard) is the analytical standard of MNI137 (HY-103572). This product is intended for research and analytical applications. MNI137 is a potent and selective negative allosteric modulator for group II mGluRs. MNI137 has IC50s values of 8.3 and 12.6 nM for human and rat mGlu2 inhibition of glutamate-induced calcium mobilization. -
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Terephthalic acid impurity 1 (Standard)
0 ImagesCat. No.: HY-W837678RCAS No.: 29278-67-9O,O-(Butane-1,4-diyl) bis(4-hydroxybutyl) diterephthalate (Standard) is the analytical standard of O,O-(Butane-1,4-diyl) bis(4-hydroxybutyl) diterephthalate. This product is intended for research and analytical applications. -
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FX1 (Standard)
0 ImagesCat. No.: HY-102027RCAS No.: 1426138-42-2 -
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Ombitasvir (Standard)
0 ImagesSynonyms: ABT-267 (Standard)Ombitasvir (Standard) is the analytical standard of Ombitasvir. This product is intended for research and analytical applications. Ombitasvir is a potent inhibitor of the hepatitis C virus protein NS5A, with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a. -
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KI696 (Standard)
0 ImagesCat. No.: HY-101140RCAS No.: 1799974-70-1KI696 (Standard) is the analytical standard of KI696 (HY-101140). This product is intended for research and analytical applications. KI696 is a selective KEAP1/NRF2 protein-protein interaction inhibitor with a human Kd value of 1.3 nM. KI696 acts by competitively occupying the NRF2-binding pocket of the KEAP1 Kelch domain. KI696 blocks KEAP1-mediated ubiquitination and degradation of NRF2, promotes the translocation of NRF2 to the nucleus, activates the expression of downstream antioxidant genes, increases intracellular glutathione levels, and alleviates oxidative stress-induced cell damage and inflammatory cell infiltration in the lungs. KI696 reduces ozone-induced pulmonary oxidative damage and inflammatory cell accumulation in rats, and upregulates pulmonary antioxidant genes. KI696 can be used in research related to chronic obstructive pulmonary disease, oxidative stress and inflammation. -
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Oxyphencyclimine hydrochloride (Standard)
0 ImagesOxyphencyclimine (hydrochloride) (Standard) is the analytical standard of Oxyphencyclimine (hydrochloride). This product is intended for research and analytical applications. A new tertiary amine, Oxyphencyclimine hydrochloride,has been investigated for its effects on the peripheral parasympathetic system. -
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Arg-Gly-Asp-Ser (Standard)
0 ImagesSynonyms: RGDS peptide (Standard); Fibronectin tetrapeptide (Standard)Arg-Gly-Asp-Ser (Standard) is the analytical standard of Arg-Gly-Asp-Ser. This product is intended for research and analytical applications. Arg-Gly-Asp-Ser is an integrin binding sequence that inhibits integrin receptor function. Arg-Gly-Asp-Ser directly and specifically bind pro-caspase-8, pro-caspase-9 and pro-caspase-3, while it does not bind pro-caspase-1. -
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Transfluthrin (Standard)
0 ImagesCat. No.: HY-W075176RCAS No.: 118712-89-3Transfluthrin (Standard) is the analytical standard of Transfluthrin (HY-W075176). This product is intended for research and analytical applications. Transfluthrin is an insecticide with extremely low acute toxicity to vertebrates. Transfluthrin acts as a mosquito repellent, exerts mosquito control effects via electric heating fumigators, and is widely used in studies related to malaria, bancroftian filariasis and mosquito-borne infectious diseases. Transfluthrin may also induce adverse reactions such as pulmonary sensory irritation, sensitization, genotoxicity and respiratory depression, and can increase the concentrations and activities of CYP2E1 and CYP3A2 in rat brains. Transfluthrin can be removed from wastewater through biodegradation and activated sludge adsorption, and can be degraded by microorganisms such as Azovibrio and Tauera. -
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Antioxidant 1010 (Standard)
0 ImagesCat. No.: HY-W010653RCAS No.: 6683-19-8Synonyms: lrganox 1010 (Standard); AT1010 (Standard)Antioxidant 1010 (Standard) is the analytical standard of Antioxidant 1010 (lrganox 1010; AT1010) (HY-W010653) . This product is intended for research and analytical applications. Antioxidant 1010 is a hindered phenolic antioxidant. Antioxidant 1010 does not inhibit intercellular gap-junctional communication. Antioxidant 1010 exhibits antioxidant efficacy in plastic, rubber and synthetic fiber.. -
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5-Iodotubercidin (Standard)
0 ImagesSynonyms: NSC 113939 (Standard); 5-ITu (Standard)5-Iodotubercidin (Standard) is the analytical standard of 5-Iodotubercidin. This product is intended for research and analytical applications. 5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin. -
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1-Phenoxy-3-(propan-2-ylamino)propan-2-ol (Standard)
0 ImagesCat. No.: HY-W024531RCAS No.: 7695-63-81-Phenoxy-3-(propan-2-ylamino)propan-2-ol (Standard) is the analytical standard of 1-Phenoxy-3-(propan-2-ylamino)propan-2-ol. This product is intended for research and analytical applications. -
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2-Monostearin (Standard)
0 ImagesCat. No.: HY-W505131RCAS No.: 621-61-42-Monostearin (Standard) is the analytical standard of 2-Monostearin. This product is intended for research and analytical applications. 2-Monostearin is a biochemical reagent. -
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5H-Dibenzo[b,f]azepin-10(11H)-one (Standard)
0 ImagesCat. No.: HY-W103288RCAS No.: 21737-58-65H-Dibenzo[b,f]azepin-10(11H)-one (Standard) is the analytical standard of 5H-Dibenzo[b,f]azepin-10(11H)-one. This product is intended for research and analytical applications. -
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Ritlecitinib (Standard)
0 ImagesCat. No.: HY-100754RCAS No.: 1792180-81-4Synonyms: PF-06651600 (Standard)Ritlecitinib (Standard) is the analytical standard of Ritlecitinib (HY-100754). This product is intended for research and analytical applications. Ritlecitinib (PF-06651600) is a highly selective, orally active, irreversible covalent JAK3 inhibitor (IC50=33 nM) without inhibitory activity towards JAK1, JAK2, and TYK2 (IC50 >10 μ M). Ritlecitinib rapidly inactivates the JAK3 kinase, and blocks signaling and downstream STAT phosphorylation mediated by common gamma chain cytokines such as IL-2 and IL-15. Ritlecitinib can inhibit Th1/Th17 cell differentiation and function, and effectively suppress preclinical animal models such as alopecia areata, adjuvant-induced arthritis (AIA), and experimental autoimmune encephalomyelitis (EAE). -
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Lofexidine hydrochloride (Standard)
0 ImagesSynonyms: Baq-168 (Standard); MDL-14042 (Standard)Lofexidine (Baq-168) hydrochloride Standard is the analytical standard of Lofexidine hydrochloride (HY-B1052). This product is intended for research and analytical applications. Lofexidine hydrochloride (Baq-168) is an orally active agonist of the imidazoline I1 receptor (imidazoline I1 receptor) (Ki: 1.9 nM) and α2-adrenergic receptor (α2-adrenergic receptor). Lofexidine hydrochloride binds to the α2A-adrenergic receptor, reduces sympathetic outflow, lowers blood pressure, and exhibits vasoconstrictive effects. Lofexidine hydrochloride regulates the expression of c-fos and alleviates opioid withdrawal symptoms. Lofexidine hydrochloride is applicable to research on opioid addiction and withdrawal. -
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Brevifolincarboxylic acid (Standard)
0 ImagesCat. No.: HY-N4095RCAS No.: 18490-95-4Brevifolincarboxylic acid (Standard) is the analytical standard of Brevifolincarboxylic acid (HY-N4095). This product is intended for research and analytical applications. Brevifolincarboxylic acid is a phenolic compound. Brevifolincarboxylic acid can be isolated from Duchesnea chrysantha. Brevifolincarboxylic acid inhibits α-glucosidase with an IC50 value of 323.46 μM. Brevifolincarboxylic acid has an inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarbacid scavenges ROS. Brevifolincarbacid restores the glucose uptake activity of myotubes. Brevifolincarboxylic acid has antitumor activity against lung and gastric cancer. Brevifolincarbacid can be used in the study of diabetes and inflammatory diseases. -
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LY367385 hydrochloride (Standard)
0 ImagesCat. No.: HY-107515ARCAS No.: 2829282-00-8LY367385 hydrochloride (Standard) is the analytical standard of LY367385 (hydrochloride) (HY-107515A). This product is intended for research and analytical applications. LY367385 hydrochloride is a highly selective and potent mGluR1a antagonist. LY367385 hydrochloride has an IC50 of 8.8 μM for inhibiting of quisqualate-induced phosphoinositide (PI) hydrolysis, compared with >100 μM for mGlu5a. LY367385 hydrochloride has neuroprotective, anticonvulsant and antiepileptic effects. -
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(S)-Ponesimod (Standard)
0 ImagesCat. No.: HY-Z0676RCAS No.: 854111-49-2(Z)-5-((Z)-3-chloro-4-((S)-2,3-dihydroxypropoxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one (Standard) is the analytical standard of (Z)-5-((Z)-3-chloro-4-((S)-2,3-dihydroxypropoxy)benzylidene)-2-(propylimino)-3-(o-tolyl)thiazolidin-4-one. This product is intended for research and analytical applications. -
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- 3,5-Dihydroxy-4-methoxybenzoic acid (Standard)
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(S)-Salsolinol (Standard)
0 ImagesCat. No.: HY-113316BRCAS No.: 27740-96-1Synonyms: (-)-Salsolinol (Standard)(S)-Salsolinol (Standard) is the analytical standard of (S)-Salsolinol. This product is intended for research and analytical applications. (S)-Salsolinol ((-)-Salsolinol) is a dopamine-derived endogenous metabolite. -
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