2. Signaling Pathways
  3. Protein Tyrosine Kinase/RTK
  4. SHP2
  5. SHP2 Degrader

SHP2 Degrader

SHP2 Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-W584514
    Thalidomide-NH-(CH2)2-NH2 TFA
    		Degrader
    Thalidomide-NH-(CH2)2-NH2 TFA is an alkyl-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN proteins. Thalidomide-NH-(CH2)2-NH2 TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules designed to synthesize small PROTAC molecules targeting SHP2 protein.