ABD56
ABD56 is a compound that induces osteoclast apoptosis and has the activity of inhibiting osteoclast formation and inducing apoptosis. ABD56 can inhibit osteoclast formation and induce apoptosis, and its mechanism is related to the inhibition of NFκB and ERK pathways.
For research use only. We do not sell to patients.
- CAS No.: 521294-19-9
- Formula: C17H18O3
- Molecular Weight:270.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | IC50 |
>200 μM
Compound: 67, ABD56
|
Effect on apoptosis of hepatocyte
Effect on apoptosis of hepatocyte
|
[PMID: 17149877] |
| Osteoblast | IC50 |
>100 μM
Compound: 67, ABD56
|
Effect on apoptosis of osteoblast
Effect on apoptosis of osteoblast
|
[PMID: 17149877] |
| Osteoclast | IC50 |
9 μM
Compound: 67, ABD56
|
Inhibition of mouse osteoclast survival
Inhibition of mouse osteoclast survival
|
[PMID: 17149877] |
Chemical Information
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CAS No. 521294-19-9
-
Molecular Weight 270.32
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Formula C17H18O3
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SMILES
O=C(OCCCCO)C1=CC=C(C=C1)C2=CC=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)