ABD56
ABD56 is a compound that induces osteoclast apoptosis and has the activity of inhibiting osteoclast formation and inducing apoptosis. ABD56 can inhibit osteoclast formation and induce apoptosis, and its mechanism is related to the inhibition of NFκB and ERK pathways.
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- CAS. Nr.: 521294-19-9
- Formel: C17H18O3
- Molecular Weight:270.32
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | IC50 |
>200 μM
Compound: 67, ABD56
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Effect on apoptosis of hepatocyte
Effect on apoptosis of hepatocyte
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[PMID: 17149877] |
| Osteoblast | IC50 |
>100 μM
Compound: 67, ABD56
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Effect on apoptosis of osteoblast
Effect on apoptosis of osteoblast
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[PMID: 17149877] |
| Osteoclast | IC50 |
9 μM
Compound: 67, ABD56
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Inhibition of mouse osteoclast survival
Inhibition of mouse osteoclast survival
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[PMID: 17149877] |
Chemical Information
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CAS. Nr. 521294-19-9
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Molecular Weight 270.32
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Formel C17H18O3
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SMILES
O=C(OCCCCO)C1=CC=C(C=C1)C2=CC=CC=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
ABD56 Related Classifications
HY-122019 Related Classifications
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