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Cat. No.: HY-184992

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AKT ligand-4

AKT ligand-4 is an AKT ligand and can be used for the synthesis of PROTACs, such as AKT ligand-4 (HY-151613).

For research use only. We do not sell to patients.

Formula: C₃₀H₂₈N₆O₂
Molecular Weight:504.58

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AKT ligand-4 Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

AKT ligand-4 is an AKT ligand and can be used for the synthesis of PROTACs, such as AKT ligand-4 (HY-151613)^[1].

All Akt Isoforms :

Chemical Information

Molecular Weight 504.58
Formula C₃₀H₂₈N₆O₂
SMILES

NC1(CCC1)C(C=C2)=CC=C2N3C4=NC(C5=CC(CCC(O)=O)=CC=C5)=CC=C4N=C3C6=CC=CN=C6N
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yu X, et al. Novel Allosteric Inhibitor-Derived AKT Proteolysis Targeting Chimeras (PROTACs) Enable Potent and Selective AKT Degradation in KRAS/BRAF Mutant Cells. J Med Chem. 2022 Oct 27;65(20):14237-14260. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
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AKT ligand-4

All Akt Isoforms

Biological Activity

Description

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

AKT ligand-4 Related Classifications

HY-184992 Related Classifications

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