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Alosetron (Hydrochloride(1:X))

(Synonyms: GR 68755 (Hydrochloride(1:X)); GR 68755X (Hydrochloride(1:X)))
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Based on 1 publication(s) in Google Scholar

Alosetron (GR 68755) Hydrochloride(1:X) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride(1:X) is used for the research of irritable bowel syndrome (IBS). Alosetron Hydrochloride(1:X) blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ~55 nM. Alosetron Hydrochloride(1:X) attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects.

For research use only. We do not sell to patients.

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  • Alosetron (Hydrochloride(1:X)) Chemical Structure
    Alosetron (Hydrochloride(1:X)) Chemical Structure
CAS No.: 132414-02-9
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  • Alosetron (Hydrochloride(1:X)) Chemical Structure
    Alosetron (Hydrochloride(1:X)) Chemical Structure
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  • Alosetron (Hydrochloride(1:X))