AMRI-59
AMRI-59 is a potent inhibitor of PrxI used for parasitic infections. AMRI-59 can increase cellular ROS, leading to activation of signaling pathways mediated by mitochondria and apoptosis signal-regulated kinase 1, thereby leading to apoptosis in A549 human lung adenocarcinoma. AMRI-59 exhibits significant antitumor activity without apparent acute toxicity.
For research use only. We do not sell to patients.
- CAS No.: 923515-92-8
- Formula: C25H27N3O2
- Molecular Weight:401.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
PrxI[1]
Chemical Information
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CAS No. 923515-92-8
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Molecular Weight 401.50
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Formula C25H27N3O2
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SMILES
O=C(N1CCC(CC2=CC=C(N3C=CC=C3)C=C2)CC1)NC4=CC=CC(C(C)=O)=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AMRI-59 Related Classifications
HY-111125 Related Classifications
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