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Cat. No.: HY-N0675

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Anhydrovinblastine

Anhydrovinblastine is a monoterpenoid indole alkaloid that can be isolated from Catharanthus roseus leaves.

For research use only. We do not sell to patients.

CAS No.: 38390-45-3
Formula: C₄₆H₅₆N₄O₈
Molecular Weight:792.96

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Anhydrovinblastine Chemical Structure

CAS No.: 38390-45-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Anhydrovinblastine is a monoterpenoid indole alkaloid that can be isolated from Catharanthus roseus leaves^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	75 nM Compound: 4a	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 22247789]
HCT-116/VM46	IC₅₀	600 nM Compound: 4a	Cytotoxicity against human vinblastin-resistant HCT116/VM46 cells Cytotoxicity against human vinblastin-resistant HCT116/VM46 cells	[PMID: 22247789]
HepG2	IC₅₀	4.53 μM Compound: 14	Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 26522953]
KB	IC₅₀	2.06 μM Compound: 14	Cytotoxicity against human KB cells after 72 hrs by SRB assay Cytotoxicity against human KB cells after 72 hrs by SRB assay	[PMID: 26522953]
L1210	IC₅₀	65 nM Compound: 4a	Cytotoxicity against mouse L1210 cells Cytotoxicity against mouse L1210 cells	[PMID: 22247789]
Lu1	IC₅₀	5.98 μM Compound: 14	Cytotoxicity against human Lu1 cells after 72 hrs by SRB assay Cytotoxicity against human Lu1 cells after 72 hrs by SRB assay	[PMID: 26522953]
MCF7	IC₅₀	4.63 μM Compound: 14	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 26522953]

Chemical Information

CAS No. 38390-45-3
Molecular Weight 792.96
Formula C₄₆H₅₆N₄O₈
SMILES

CC[C@]1([C@H]2OC(C)=O)[C@@]3([H])[C@](C(C4=C5)=CC([C@](C6=C7C8=CC=CC=C8N6)(C[C@](C=C9CC)([H])C[N@@](C9)CC7)C(OC)=O)=C5OC)(CCN3CC=C1)[C@](N4C)([H])[C@@]2(O)C(OC)=O
Structure Classification
- Alkaloids
- Indole Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. TrevorKidd, et al. Inter-organ transport of secologanin allows assembly of monoterpenoid

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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