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Art. -Nr.: HY-N0675

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Anhydrovinblastine

Anhydrovinblastine is a monoterpenoid indole alkaloid that can be isolated from Catharanthus roseus leaves.

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CAS. Nr.: 38390-45-3
Formel: C₄₆H₅₆N₄O₈
Molecular Weight:792.96

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Anhydrovinblastine Chemical Structure

CAS. Nr.: 38390-45-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Anhydrovinblastine is a monoterpenoid indole alkaloid that can be isolated from Catharanthus roseus leaves^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HCT-116	IC₅₀	75 nM Compound: 4a	Cytotoxicity against human HCT116 cells Cytotoxicity against human HCT116 cells	[PMID: 22247789]
HCT-116/VM46	IC₅₀	600 nM Compound: 4a	Cytotoxicity against human vinblastin-resistant HCT116/VM46 cells Cytotoxicity against human vinblastin-resistant HCT116/VM46 cells	[PMID: 22247789]
HepG2	IC₅₀	4.53 μM Compound: 14	Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay Cytotoxicity against human HepG2 cells after 72 hrs by SRB assay	[PMID: 26522953]
KB	IC₅₀	2.06 μM Compound: 14	Cytotoxicity against human KB cells after 72 hrs by SRB assay Cytotoxicity against human KB cells after 72 hrs by SRB assay	[PMID: 26522953]
L1210	IC₅₀	65 nM Compound: 4a	Cytotoxicity against mouse L1210 cells Cytotoxicity against mouse L1210 cells	[PMID: 22247789]
Lu1	IC₅₀	5.98 μM Compound: 14	Cytotoxicity against human Lu1 cells after 72 hrs by SRB assay Cytotoxicity against human Lu1 cells after 72 hrs by SRB assay	[PMID: 26522953]
MCF7	IC₅₀	4.63 μM Compound: 14	Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay Cytotoxicity against human MCF7 cells after 72 hrs by SRB assay	[PMID: 26522953]

Chemical Information

CAS. Nr. 38390-45-3
Molecular Weight 792.96
Formel C₄₆H₅₆N₄O₈
SMILES

CC[C@]1([C@H]2OC(C)=O)[C@@]3([H])[C@](C(C4=C5)=CC([C@](C6=C7C8=CC=CC=C8N6)(C[C@](C=C9CC)([H])C[N@@](C9)CC7)C(OC)=O)=C5OC)(CCN3CC=C1)[C@](N4C)([H])[C@@]2(O)C(OC)=O
Structure Classification
- Alkaloids
- Indole Alkaloids
Initial Source
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. TrevorKidd, et al. Inter-organ transport of secologanin allows assembly of monoterpenoid

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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