Antifungal agent 122
Antifungal agent 122 (compound 201) is a potent and broad-spectrum antifungal agent. Antifungal agent 122 prevents fungal phase transition and the formation of fungal biofilm. Antifungal agent 122 inhibits CYP3A4-M and CYP3A4-T enzyme activity with IC50 values of 2.11, 4.53 µM. Antifungal agent 122 shows no cytotoxicity.
For research use only. We do not sell to patients.
- CAS No.: 3054212-80-2
- Formula: C28H24F4N4O
- Molecular Weight:508.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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CYP3A4-M 2.11 μM (IC50) |
CYP3A4-T 4.53 μM (IC50) |
Chemical Information
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CAS No. 3054212-80-2
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Molecular Weight 508.51
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Formula C28H24F4N4O
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SMILES
FC1=CC=C([C@@]([C@H](N(C)CC2=CC=C(C#CC3=CC=C(F)C=C3F)C=C2)C)(O)CN4N=CN=C4)C(F)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)