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Cat. No.: HY-184376

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Antiparasitic agent-43

Antiparasitic agent-43 is a pyrazine derivative and a Plasmodium falciparum inhibitor with in vitro and in vivo antimalarial activity. It inhibits the growth of P. falciparum in vitro and can be used in research related to malaria.

For research use only. We do not sell to patients.

CAS No.: 2095562-44-8
Formula: C₂₀H₁₈FN₅O
Molecular Weight:363.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Antiparasitic agent-43 Chemical Structure

CAS No.: 2095562-44-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
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Bioz

Biological Activity

Description

All Parasite Isoforms :

In Vitro

Antiparasitic agent-43 (Example 1) (24 h) potently inhibits the in vitro growth of *Plasmodium falciparum* Pf3D7, with a mean IC₅₀ value of 0.025 μM ^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2095562-44-8
Molecular Weight 363.39
Formula C₂₀H₁₈FN₅O
SMILES

O=C(N1CCNCC1)C2=CC=C(C3=NC(C4=CC(F)=CN=C4)=CN=C3)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Rosse G. Pyrazine Analogs for the Treatment of Protozoal Infections. ACS Med Chem Lett. 2017 Jul 19;8(8):789. [Content Brief]

[2]. Zhou Yaming, et al. Pharmaceutical composition for preventing or treating alopecia. WO2017178828A1. World Intellectual Property Organization. 2017-10-19.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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Antiparasitic agent-43

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Antiparasitic agent-43 Related Classifications

HY-184376 Related Classifications