Antiparasitic agent-7
Antiparasitic agent-7 (compound 5d) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.85 μM. Antiparasitic agent-7 also has certain cytotoxicity against HepG2 (CC50 = 10.61 μM).
For research use only. We do not sell to patients.
- CAS No.: 2253996-75-5
- Formula: C18H15N3O5
- Molecular Weight:353.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
IC50: 2.85 μM (L. infantum)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
10.61 μM
Compound: 5d
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
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[PMID: 32590115] |
| HFF-1 | CC50 |
42.2 μM
Compound: 5d
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Cytotoxicity against human HFF-1 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
Cytotoxicity against human HFF-1 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
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[PMID: 32590115] |
Chemical Information
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CAS No. 2253996-75-5
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Molecular Weight 353.33
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Formula C18H15N3O5
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SMILES
OC(C(C1=NC(C2=CC=C(OC)C=C2)=NO1)=C)C3=C(C=CC=C3)[N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antiparasitic agent-7 Related Classifications
HY-146045 Related Classifications
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