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製品番号: HY-169746

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Antiviral agent 63

Antiviral agent 63 is a nucleoside analog with anti-HCV activity. Antiviral agent 63 can inhibit viral replication by inhibiting the activity of HCV RNA-dependent RNA polymerase or other virus-related enzymes.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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CAS 番号: 1613591-70-0
分子式: C₂₅H₃₃F₂N₆O₈P
分子量:614.54

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Antiviral agent 63 構造式

CAS 番号: 1613591-70-0

容量

価格（税別）

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数量

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

IC₅₀ & Target

RNA Polymerase

DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
A549	CC₅₀	>100 μM Compound: 40	Cytotoxicity against human A549 cells incubated for 8 days by cellTiter-Glo assay Cytotoxicity against human A549 cells incubated for 8 days by cellTiter-Glo assay	[PMID: 32816483]
HeLa	CC₅₀	>100 μM Compound: 40	Cytotoxicity against human HeLa cells incubated for 8 days by cellTiter-Glo assay Cytotoxicity against human HeLa cells incubated for 8 days by cellTiter-Glo assay	[PMID: 32816483]
HepG2	CC₅₀	>100 μM Compound: 40	Cytotoxicity against human HepG2 cells incubated for 8 days by cellTiter-Glo assay Cytotoxicity against human HepG2 cells incubated for 8 days by cellTiter-Glo assay	[PMID: 32816483]
Huh-7	CC₅₀	>100 μM Compound: 40	Cytotoxicity against human HuH7 cells incubated for 8 days by cellTiter-Glo assay Cytotoxicity against human HuH7 cells incubated for 8 days by cellTiter-Glo assay	[PMID: 32816483]
Huh-7	CC₅₀	>100 μM Compound: 40	Cytotoxicity against human HuH7 cells infected with HCV con1 subgenomic replicon assessed as reduction in cell viability measured after 3 days by CellTiter-blue cell viability assay Cytotoxicity against human HuH7 cells infected with HCV con1 subgenomic replicon assessed as reduction in cell viability measured after 3 days by CellTiter-blue cell viability assay	[PMID: 32816483]
Huh-7	EC₅₀	0.014 μM Compound: 40	Antiviral activity against HCV con1 subgenomic replicon infected in human HuH7 cells assessed as reduction in viral RNA level by qRT-PCR analysis Antiviral activity against HCV con1 subgenomic replicon infected in human HuH7 cells assessed as reduction in viral RNA level by qRT-PCR analysis	[PMID: 32816483]
MT4	CC₅₀	92 μM Compound: 40	Cytotoxicity against human MT4 cells incubated for 8 days by cellTiter-Glo assay Cytotoxicity against human MT4 cells incubated for 8 days by cellTiter-Glo assay	[PMID: 32816483]
U-937	CC₅₀	10 μM Compound: 40	Cytotoxicity against human U937 cells incubated for 8 days by cellTiter-Glo assay Cytotoxicity against human U937 cells incubated for 8 days by cellTiter-Glo assay	[PMID: 32816483]

化学情報

CAS 番号 1613591-70-0
分子量 614.54
分子式 C₂₅H₃₃F₂N₆O₈P
SMILES

C[C@@]1([C@@H](O[C@@](F)([C@H]1O)COP(OC2=CC=CC=C2)(N[C@@H](C)C(OC(C)C)=O)=O)N3C4=NC(N)=NC(OCC)=C4N=C3)F
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (271 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Beigelman et al, Preparation of substituted nucleosides, nucleotides and analogs thereof as antitumor and HCV antiviral agents, WO2014100505, US, 2014-06-26.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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生物活性
- 製品説明
- IC₅₀ & Target
化学情報
純度とドキュメンテーション
参考文献

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Antiviral agent 63

DNA/RNA Synthesis アイソフォーム固有の製品をすべて表示

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Antiviral agent 63 関連分類

HY-169746 関連分類