Arbekacin
Arbekacin, an aminoglycoside antibiotic, exhibits broad antimicrobial activities against not only Gram-positive bacteria but also Gram-negative bacteria.
For research use only. We do not sell to patients.
- CAS No.: 51025-85-5
- Formula: C22H44N6O10
- Molecular Weight:552.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Arbekacin potently inhibits Acinetobacter baumannii. (MIC50=2 μg/mL) and Enterobacteriaceae from PHP (MIC50=0.25-2 μg/mL; MIC90=1-8 μg/mL)[1].
Arbekacin also inhibits worldwide well-characterized MDR Gram-negative and MRSA strains[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 51025-85-5
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Molecular Weight 552.62
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Formula C22H44N6O10
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SMILES
O[C@H]1[C@H](O[C@@H]2[C@@H](CC[C@@H](O2)CN)N)[C@@H](N)C[C@@H](NC([C@@H](O)CCN)=O)[C@@H]1O[C@H]3O[C@H](CO)[C@H](O)[C@H](N)[C@H]3O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Matsumoto T. Arbekacin: another novel agent for treating infections due to methicillin-resistant Staphylococcus aureus and multidrug-resistant Gram-negative pathogens. Clin Pharmacol. 2014 Sep 26;6:139-48. [Content Brief]
[2]. Sader HS, et al. Arbekacin activity against contemporary clinical bacteria isolated from patients hospitalized with pneumonia. Antimicrob Agents Chemother. 2015;59(6):3263-70. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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