2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. Aromatase-IN-3

Aromatase-IN-3 (compound 7d) is an aromatase inhibitor with an IC50 of 54 nM. Through suppressing the conversion of androstenedione to oestrogen caused by aromatase, Aromatase-IN-3 exerts an appreciable tumor growth inhibitory activities against breast cancer cell lines, suggesting its usage for ER+ cancer research.

For research use only. We do not sell to patients.

Aromatase-IN-3 Chemical Structure

Aromatase-IN-3 Chemical Structure

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Aromatase-IN-3 Related Antibodies

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Description

Aromatase-IN-3 (compound 7d) is an aromatase inhibitor with an IC50 of 54 nM. Through suppressing the conversion of androstenedione to oestrogen caused by aromatase, Aromatase-IN-3 exerts an appreciable tumor growth inhibitory activities against breast cancer cell lines, suggesting its usage for ER+ cancer research[1].

IC50 & Target[1]

Aromatase

54 nM (IC50)

Molecular Weight

570.72

Formula

C38H38N2O3
SMILES

O=C(C(OCC)=O)C1=CN(CCCCCNC2=CC=C(/C(C3=CC=CC=C3)=C(C4=CC=CC=C4)\C)C=C2)C5=C1C=CC=C5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Aromatase-IN-3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Aromatase-IN-3Cytochrome P450CYPsAromatase Inhibitorandrostenedioneoestrogenbreast cancerER+ cancerInhibitorinhibitorinhibit

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