Asperaculane B
Asperaculane B is a fungal metabolite against P. falciparum transmission with an IC50 of 7.89 µM. Asperaculane B also inhibits the development of asexual P. falciparum with IC50 of 3 µM, and it is nontoxic to human cells.
For research use only. We do not sell to patients.
- CAS No.: 2378379-27-0
- Formula: C14H20O3
- Molecular Weight:236.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
Plasmodium |
Microbial Metabolite |
In Vitro
Asperaculane B is a new dual-functional antimalarial lead that has the potential to treat malaria and block malaria transmission[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2378379-27-0
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Molecular Weight 236.31
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Formula C14H20O3
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SMILES
CCC1=CC([C@]2(C)[C@@H]1CC=C(CO)C[C@@H]2O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)