1. Anti-infection
  2. Bacterial Antibiotic
  3. Aspoxicillin

Aspoxicillin 

Cat. No.: HY-135842 Purity: 99.56%
COA Handling Instructions

Aspoxicillin is a broad-spectrum antimicrobial agent against 68 isolates of Actinobacillus pleuropneumoniae with an MIC90 value of <= 0.05 μg/ml. Aspoxicillin has a long half-life in mouse serum of 55 minutes.

For research use only. We do not sell to patients.

Aspoxicillin Chemical Structure

Aspoxicillin Chemical Structure

CAS No. : 63358-49-6

Size Price Stock Quantity
5 mg USD 43 In-stock
10 mg USD 65 In-stock
25 mg USD 130 In-stock
50 mg USD 210 In-stock
100 mg USD 340 In-stock
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500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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  • Biological Activity

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Description

Aspoxicillin is a broad-spectrum antimicrobial agent against 68 isolates of Actinobacillus pleuropneumoniae with an MIC90 value of <= 0.05 μg/ml. Aspoxicillin has a long half-life in mouse serum of 55 minutes[1][2].

IC50 & Target

β-lactam

 

In Vitro

Aspoxicillin is a semisynthetic penicillin derivative[2] Aspoxicillin induces postantibiotic effects (PAEs) against Staphylococcus aureus Smith of 1.7 h in vitro[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Aspoxicillin induces PAEs against Staphylococcus aureus Smith of 5.2 h in vivo in a thigh infection model in neutropenic mice[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

493.53

Appearance

Solid

Formula

C21H27N5O7S

CAS No.
SMILES

O=C([C@@H](C(C=C1)=CC=C1O)NC([C@H](N)CC(NC)=O)=O)N[C@H]2[C@](SC(C)3C)([H])N(C2=O)[C@H]3C(O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 25 mg/mL (50.66 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0262 mL 10.1311 mL 20.2622 mL
5 mM 0.4052 mL 2.0262 mL 4.0524 mL
10 mM 0.2026 mL 1.0131 mL 2.0262 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 12.5 mg/mL (25.33 mM); Clear solution; Need ultrasonic

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Aspoxicillin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Aspoxicillin
Cat. No.:
HY-135842
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