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Art. -Nr.: HY-156562B

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5-PT TFA

(Synonyms: 5-Propargyltryptamide TFA)

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5-PT (5-Propargyltryptamide) TFA is an alkyne-functionalized derivative of 5-HT (HY-B1473A) and serotonylation substrate that can be taken up by living cells. After conjugation with biotin, 5-PT TFA enables the identification of serotonylated proteins via copper click chemistry and mass spectrometry. 5-PT TFA can label and isolate serotonylated cells in alveolar epithelial cells for proteomic analysis. 5-PT TFA is applicable to research related to bronchopulmonary dysplasia.

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CAS. Nr.: 3117303-22-4
Formel: C₁₅H₁₅F₃N₂O₃
Molecular Weight:328.29

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5-PT TFA Chemical Structure

CAS. Nr.: 3117303-22-4

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Bioz

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Beschreibung

In Vitro

5-PT (100 μM; 24 h) TFA labels 121 unique serotonylated proteins in MLE-12 alveolar epithelial cells, with many of these proteins linked to cellular processes and cell behavior regulation^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3117303-22-4
Molecular Weight 328.29
Formel C₁₅H₁₅F₃N₂O₃
SMILES

O=C(C(F)(F)F)O.C#CCOC1=CC2=C(NC=C2CCN)C=C1
Synonyms

5-Propargyltryptamide TFA
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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iScience

5-HT promotes bronchopulmonary dysplasia via TGM2-mediated serotonylation. [Abstract]

2025 Nov 19;28(12):114120. PMID: 41438086

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Handling Instructions (2659 KB)

Verweise

[1]. Cai P, Ding R, Yin C, et al.. 5-HT promotes bronchopulmonary dysplasia via TGM2-mediated serotonylation. iScience. 2025 Dec 19;28(12):114120. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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5-PT TFA

1 Cited Publications

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5-PT TFA

Publications Citing Use of MedChemExpress (MCE) 5-PT TFA

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5-PT TFA Related Classifications

HY-156562B Related Classifications