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Art. -Nr.: HY-42849

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Sultopride

Name: Sultopride
Brand: MedChemExpress
SKU: HY-42849
Availability: PreOrder

(Synonyms: LIN-1418)

1 Cited Publications

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Sultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor.

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CAS. Nr.: 53583-79-2
Formel: C₁₇H₂₆N₂O₄S
Molecular Weight:354.46

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Sultopride Chemical Structure

CAS. Nr.: 53583-79-2

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Biologische Aktivität

Beschreibung

Sultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor.

IC₅₀ & Target

Dopamine D2 receptor^[1]

Alle Dopamine Receptor Isoform-spezifische Produkte anzeigen :

In Vivo

Sultopride (LIN-1418) is a selective antagonist of dopamine D2 receptor. DOPAC and HVA levels in the striatum, the nucleus accumbens and the medial prefrontal cortex are higher in the rats treated with Sultopride and sulpiride than those of the controls. In the striatum, DOPAC and HVA levels are higher in the Sultopride-treated rats than the sulpiride-treated rats (p<0.05). In the nucleus accumbens, DOPAC levels are higher in the Sultopride-treated rats than sulpiride treated rats (p<0.05). In the Sultopride-treated rats, DOPAC and HVA levels are higher in the striatum or in the nucleus accumbens than in the medial prefrontal cortex (p<0.05)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 53583-79-2
Molecular Weight 354.46
Formel C₁₇H₂₆N₂O₄S
SMILES

O=C(NCC1N(CC)CCC1)C2=CC(S(=O)(CC)=O)=CC=C2OC
Synonyms

LIN-1418
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Acta Pharmacol Sin

Isosibiricin inhibits microglial activation by targeting the dopamine D1/D2 receptor-dependent NLRP3/caspase-1 inflammasome pathway. [Abstract]

2020 Feb;41(2):173-180. PMID: 31506572

Reinheit & Dokumentation

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Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Moriuchi K, et al. Differences in effects of sultopride and sulpiride on dopamine turnover in rat brain. Neurochem Res. 1995 Jan;20(1):95-9. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

Sultopride

1 Cited Publications

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Sultopride

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