Ainsliadimer A
Ainsliadimer A is a sesquiterpene lactone dimer with an unusual carbon skeleton. Ainsliadimer A can be obtained from from Ainsliaea macrocephala. Ainsliadimer A inhibits the production of nitric oxide in cells stimulated by LPS.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1039431-94-1
- Formel: C30H34O7
- Molecular Weight:506.59
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| C6 | IC50 |
4.3 μM
Compound: 8
|
Cytotoxicity against rat C6 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
Cytotoxicity against rat C6 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
|
[PMID: 34496568] |
| HCCLM3 | IC50 |
>10 μM
Compound: 8
|
Cytotoxicity against human HCCLM3 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
Cytotoxicity against human HCCLM3 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
|
[PMID: 34496568] |
| HeLa | IC50 |
5.3 μM
Compound: 8
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
|
[PMID: 34496568] |
| Huh-7 | IC50 |
4.4 μM
Compound: 8
|
Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
|
[PMID: 34496568] |
| PANC-1 | IC50 |
9.9 μM
Compound: 8
|
Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
Cytotoxicity against human PANC-1 cells assessed as reduction in cell viability incubated for 72 hrs by Celltiter-Glo assay
|
[PMID: 34496568] |
| RAW264.7 | IC50 |
2.41 μg/mL
Compound: 114
|
Anti-inflammatory activity in LPS induced mouse RAW264.7 cells assessed as inhibition of NO production
Anti-inflammatory activity in LPS induced mouse RAW264.7 cells assessed as inhibition of NO production
|
[PMID: 32688203] |
Chemical Information
-
CAS. Nr. 1039431-94-1
-
Molecular Weight 506.59
-
Formel C30H34O7
-
SMILES
O[C@@]1(C[C@](C(CC2)=C)([H])[C@@]3([H])[C@](OC4=O)([H])[C@]2([H])C4=C)[C@](CC[C@@]13O)(C5=O)[C@]([C@@](C6=C)([H])C5)([H])[C@](OC7=O)([H])[C@](CC6)([H])C7=C
-
Structure Classification
-
Initial Source
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Ainsliadimer A Related Classifications
HY-N12478 Related Classifications
Powered by Bioz