Anserinone B
Anserinone B is an antifungal and antibacterial benzoquinone. Anserinone B causes radial growth reductions of 50% and 37% against S.fimicola and A. furfuraceus, respectively. Anserinones B also displays moderate cytotoxicity in the NCI’s 60 human tumor cell line panel (GI50=4.4 µg/mL).
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- CAS. Nr.: 190895-96-6
- Formel: C11H14O4
- Molecular Weight:210.23
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Microbial Metabolite |
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| C6 | IC50 |
<10 μM
Compound: 8
|
Cytotoxicity against rat C6 cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
Cytotoxicity against rat C6 cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
|
[PMID: 34787427] |
| HGC-27 | IC50 |
<10 μM
Compound: 8
|
Cytotoxicity against human HGC-27 cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
Cytotoxicity against human HGC-27 cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
|
[PMID: 34787427] |
| MDA-MB-435 | IC50 |
3.6 μg/mL
Compound: 2
|
Cytotoxicity against human MDA-MB-435 after 48 hrs by SRB assay
Cytotoxicity against human MDA-MB-435 after 48 hrs by SRB assay
|
[PMID: 15043411] |
| SH-SY5Y | IC50 |
<10 μM
Compound: 8
|
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability measured for 48 hrs by CCK colorimetric assay
|
[PMID: 34787427] |
Chemical Information
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CAS. Nr. 190895-96-6
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Molecular Weight 210.23
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Formel C11H14O4
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SMILES
O=C(C=C1OC)C(C)=C(C[C@H](O)C)C1=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)