Anticancer agent 128
Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently targets the BIR3 domains of XIAP, cIAP1, and cIAP2. Anticancer agent 128 targets the BIR3 domains of XIAP, cIAP1, and cIAP2 with IC50s of 24.9 nM, 19.3 nM, and 10.3 nM, respectively.
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- CAS. Nr.: 2941243-62-3
- Formel: C26H38N4O4
- Molecular Weight:470.60
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
IC50: 27.2 nM (XIAP-BIR3), 16.6 nM (cIAP1-BIR3), and 8.4 nM (cIAP2-BIR3)[1]
Chemical Information
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CAS. Nr. 2941243-62-3
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Molecular Weight 470.60
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Formel C26H38N4O4
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SMILES
O=C(N1[C@H](C(N[C@H]2C(C=CC=C3O)=C3CC2)=O)CCC1)[C@H](C4CCCCC4)NC([C@H](C)NC)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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