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Art. -Nr.: HY-160286

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BI-7190

BI-7190 is a selective BPTF inhibitor (K_d = 3.5 nM). BI-7190 can be used in the research of cancer.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

The BI-7190 was designed by Boehringer Ingelheim and could be obtained free of charge through the Boehringer Ingelheim open innovation portal opnMe.com, associated with its negative control.

CAS. Nr.: 2001082-11-5
Formel: C₂₃H₃₁N₃O₂
Molecular Weight:381.52

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

BI-7190 Chemical Structure

CAS. Nr.: 2001082-11-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

BI-7190 is a selective BPTF inhibitor (K_d = 3.5 nM). BI-7190 can be used in the research of cancer^[1]^[2].

IC₅₀ & Target

K_d = 3.5 nM (BPTF)^[1]

Alle SWI/SNF Complex Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 2001082-11-5
Molecular Weight 381.52
Formel C₂₃H₃₁N₃O₂
SMILES

O=C1C(=C(C(=CN1C)C=2C=CC(=C(OC)C2)C3(N4CCN(C)CC4)CC3)C)C
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Buchholz C R. Chemical Probe Development for Bromodomain and PHD Finger-containing Transcription Factor (BPTF) Reader Domains as Anti-Cancer Therapy[D]. University of Minnesota, 2023.

[2]. Martinelli P, et al. Discovery of a Chemical Probe to Study Implications of BPTF Bromodomain Inhibition in Cellular and in vivo Experiments. ChemMedChem. 2023 Mar 14;18(6):e202200686. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise

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BI-7190

Alle SWI/SNF Complex Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

BI-7190 Related Classifications

HY-160286 Related Classifications