CDK8-IN-18
CDK8-IN-18 (compound BRD-2299) is a potent inhibitor of CDK8, with the IC50 of 43 μM. CDK8-IN-18 plays an important role in cancer research.
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- CAS. Nr.: 642002-74-2
- Formel: C16H18N4
- Molecular Weight:266.34
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
IC50 & Target
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CDK8 43 μM (IC50) |
Chemical Information
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CAS. Nr. 642002-74-2
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Molecular Weight 266.34
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Formel C16H18N4
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SMILES
N#CC1=C(C2=CN=CC=C2)C(CC)=C(CCC)N=C1N
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Protokoll
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)