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CDX-3379

(Synonyms: KTN-3379)

CDX-3379 is a humanized monoclonal antibody inhibitor targeting ErbB3. CDX-3379 binds to ErbB3, blocking the dimerization of ErbB3 with other receptors, thereby inhibiting the phosphorylation of ErbB3. CDX-3379 can inhibit the growth and proliferation of tumor cells. CDX-3379 is promising for research of tumors expressing ErbB3 and NRG1, such as HNSCC.

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  • Reinheit: 99.38%
  • CAS. Nr.: 2070921-00-3
  • Molecular Weight:143.36 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for CDX-3379
  • CDX-3379 Chemical Structure
    CDX-3379 Chemical Structure
CAS. Nr.: 2070921-00-3
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CDX-3379 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
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Assay Types
  • 1/16

    Immobilized ERBB3-hFc can bind CDX-3379. The EC50 for this effect is 61.5 ng/mL.

  • CDX-3379 Chemical Structure
    1/16
  • CDX-3379
  • Immobilized ERBB3-hFc can bind CDX-3379. The EC50 for this effect is 61.5 ng/mL.