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Art. -Nr.: HY-16678

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Helioxanthin

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Helioxanthin (ACH126447) has in vitro antiviral activity with an EC₅₀ of 1 μM against HBV and is also active against flaviviruses.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 99.76%
CAS. Nr.: 18920-47-3
Formel: C₂₀H₁₂O₆
Molecular Weight:348.31

Speicherung:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Helioxanthin Chemical Structure

CAS. Nr.: 18920-47-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Helioxanthin (ACH126447) has in vitro antiviral activity with an EC₅₀ of 1 μM against HBV and is also active against flaviviruses.

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2 2.2.15	CC₅₀	6 μM Compound: 7; HE-145	Cytotoxicity against human HepG2(2.2.15) cells assessed as reduction in cell viability after 3 days by methylene blue assay Cytotoxicity against human HepG2(2.2.15) cells assessed as reduction in cell viability after 3 days by methylene blue assay	[PMID: 28383274]

Chemical Information

CAS. Nr. 18920-47-3
Appearance Solid
Molecular Weight 348.31
Formel C₂₀H₁₂O₆
Color Off-white to yellow
SMILES

O=C1OCC2=C(C3=CC=C(OCO4)C4=C3)C5=C6OCOC6=CC=C5C=C21
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 25 mg/mL (71.78 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

2.8710 mL

14.3550 mL

28.7101 mL

5 mM

0.5742 mL

2.8710 mL

5.7420 mL

10 mM

0.2871 mL

1.4355 mL

2.8710 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (278 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Yeo H, et al. Synthesis and antiviral activity of helioxanthin analogues. J Med Chem. 2005 Jan 27;48(2):534-46. [Content Brief]

[2]. Cheng, Y. C.; Chou, C. K.; Fu, L.; Kuo, Y. H.; Yeh, S. F.; Zhu, J.; Zhu, Y. Inhibition and treatment of hepatitis B virus and flavivirus by helioxanthin and its analogues. U.S. Patent 6306899 B1, 2001.

[3]. Ying C, et al. Helioxanthin analogue 8-1 inhibits duck hepatitis B virus replication in cell culture. Antivir Chem Chemother. 2010;21(2):97-103. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	2.8710 mL	14.3550 mL	28.7101 mL	71.7751 mL
	5 mM	0.5742 mL	2.8710 mL	5.7420 mL	14.3550 mL
	10 mM	0.2871 mL	1.4355 mL	2.8710 mL	7.1775 mL
	15 mM	0.1914 mL	0.9570 mL	1.9140 mL	4.7850 mL
	20 mM	0.1436 mL	0.7178 mL	1.4355 mL	3.5888 mL
	25 mM	0.1148 mL	0.5742 mL	1.1484 mL	2.8710 mL
	30 mM	0.0957 mL	0.4785 mL	0.9570 mL	2.3925 mL
	40 mM	0.0718 mL	0.3589 mL	0.7178 mL	1.7944 mL
	50 mM	0.0574 mL	0.2871 mL	0.5742 mL	1.4355 mL
	60 mM	0.0479 mL	0.2393 mL	0.4785 mL	1.1963 mL

Keywords

100 mg

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Biologische Aktivität
- Beschreibung
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise

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Helioxanthin

Anti-Infection Compound Library

Antiviral Compound Library

Traditional Chinese Medicine Active Compound Library

Anti-Hepatitis C Virus Compound Library

Antiviral Traditional Chinese Medicine Active Compound Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Mongolian Medicine Compound Library

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Helioxanthin

Anti-Infection Compound Library

Antiviral Compound Library

Traditional Chinese Medicine Active Compound Library

Anti-Hepatitis C Virus Compound Library

Antiviral Traditional Chinese Medicine Active Compound Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Mongolian Medicine Compound Library

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Helioxanthin Related Classifications

HY-16678 Related Classifications