Isoxanthopterin
Based on 1 Customer Validation
Isoxanthopterin is a pteridine marker used to indicate xanthine oxidase activity. Isoxanthopterin is used in research on type 1 diabetes, breast cancer, and hyperphenylalaninemia.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.85%
- CAS. Nr.: 529-69-1
- Formel: C6H5N5O2
- Molecular Weight:179.14
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
In Vitro
The UV-vis spectrum of Isoxanthopterin (50 μM) shows absorption maxima at 282 and 340.01 nm, which are attributed to π→π and n→π transitions[3].
Isoxanthopterin effectively supports the growth of Alcaligenes faecalis as a sole nitrogen source[5].
Isoxanthopterin (7.8-250 μM; 24 h) exhibits cytotoxicity against confluent MCF-7 human mammary carcinoma cells, with IC50 values of 109 μM (full-range least squares fit), 119 μM (62.5-250 μM range), and 103 μM (abstract), as measured by the MTS assay[7].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:MCF-7
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Concentration:7.8-500 μM
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Incubation Time:24 h
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Result:Exhibited cytotoxicity against MCF-7 human breast cancer cells.
Chemical Information
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CAS. Nr. 529-69-1
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Appearance Solid
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Molecular Weight 179.14
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Formel C6H5N5O2
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Color Light yellow to brown
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SMILES
O=C1C(N=C2)=C(NC(N)=N1)NC2=O
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Structure Classification
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Initial Source
Morpho sulkowskyi
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
In Vitro:
H2O : 9.09 mg/mL (50.74 mM; Need ultrasonic)
H2O : 4.17 mg/mL (23.28 mM; ultrasonic and warming and adjust pH to 12 with 1 M NaOH and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (282 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| H2O / H2O | 1 mM | 5.5822 mL | 27.9111 mL | 55.8223 mL | 139.5557 mL |
| 5 mM | 1.1164 mL | 5.5822 mL | 11.1645 mL | 27.9111 mL | |
| 10 mM | 0.5582 mL | 2.7911 mL | 5.5822 mL | 13.9556 mL | |
| 15 mM | 0.3721 mL | 1.8607 mL | 3.7215 mL | 9.3037 mL | |
| 20 mM | 0.2791 mL | 1.3956 mL | 2.7911 mL | 6.9778 mL | |
| H2O | 25 mM | 0.2233 mL | 1.1164 mL | 2.2329 mL | 5.5822 mL |
| 30 mM | 0.1861 mL | 0.9304 mL | 1.8607 mL | 4.6519 mL | |
| 40 mM | 0.1396 mL | 0.6978 mL | 1.3956 mL | 3.4889 mL | |
| 50 mM | 0.1116 mL | 0.5582 mL | 1.1164 mL | 2.7911 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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