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Letaplimab

(Synonyms: IBI-188)
1 Cited Publications
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Based on 1 publication(s) in Google Scholar

Letaplimab (IBI-188) is a human IgG4 anti-CD47 monoclonal antibody. CD47 is overexpressed on cancer cells, it is a ligand for SIRPα. Letaplimab enhances tumor cell phagocytosis.

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  • Reinheit: 95.00%
  • CAS. Nr.: 2283356-07-8
  • Molecular Weight:142.38 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Letaplimab
  • Experimental Validation Results for Letaplimab
  • Letaplimab Chemical Structure
    Letaplimab Chemical Structure
CAS. Nr.: 2283356-07-8
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609-228-6898
[email protected] [email protected]
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Publications Citing Use of MedChemExpress (MCE) Letaplimab

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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Flow cytometric analysis of 1.5X106 U937 cells labeling Letaplimab (HY-P99700, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control.

  • Letaplimab Chemical Structure
    1/16
  • Letaplimab
  • Flow cytometric analysis of 1.5X106 U937 cells labeling Letaplimab (HY-P99700, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa (HY-P99003, blue) was used as the isotype control.