LTB
LTB is a prodrug formed by coupling glycolysis inhibitor (Lonidamine (HY-B0486)) with PD1/PDL1 blocker (BMS-1 (HY-19991)) by thioketal linkage. LTB can further encapsulate photosensitizer chlorine e6 (Ce6) (HY-13594) to construct a co-delivery photodynamic nanoplatform (LTB-6 NPs) by self-assembly.
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- Formel: C53H59Cl2N3O7S2
- Molecular Weight:985.09
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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Molecular Weight 985.09
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Formel C53H59Cl2N3O7S2
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SMILES
COC1=CC(OCC2=C(C(C3=CC=CC=C3)=CC=C2)C)=CC(OC)=C1CN4CCCC[C@H]4C(OCCCSC(C)(SCCCOC(C5=NN(C6=C5C=CC=C6)CC7=CC=C(C=C7Cl)Cl)=O)C)=O
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Synonyms
Lon-TK-BMS-1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
LTB Related Classifications
HY-169434 Related Classifications
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