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MitoSOX Red

312 Cited Publications
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Based on 312 publication(s) in Google Scholar

MitoSOX Red is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red.
Excitation/emission wavelength: 510/580 nm.

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  • Reinheit: 95.86%
  • CAS. Nr.: 1003197-00-9
  • Formel: C43H43IN3P
  • Molecular Weight:759.70
  • Speicherung:

    -20°C, protect from light, stored under nitrogen

    * The compound is unstable in solutions, freshly prepared is recommended.

  • MitoSOX Red Chemical Structure
    MitoSOX Red Chemical Structure
  • Experimental Validation Results for MitoSOX Red
  • Experimental Validation Results for MitoSOX Red
  • Experimental Validation Results for MitoSOX Red
  • Experimental Validation Results for MitoSOX Red
  • Experimental Validation Results for MitoSOX Red
  • Experimental Validation Results for MitoSOX Red
  • Experimental Validation Results for MitoSOX Red
CAS. Nr.: 1003197-00-9
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Cell Imaging/Staining
  • Cell Imaging/Staining
  • Cell Imaging/Staining
  • Cell Imaging/Staining
  • Cell Imaging/Staining
  • Cell Imaging/Staining
  • Cell Imaging/Staining
  • Cell Imaging/Staining
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  • MitoSOX Red Chemical Structure
    MitoSOX Red Chemical Structure
    1/16
  • 1/16

    MitoSOX Red purchased from MedChemExpress. Usage Cited in: Redox Biol. 2024 Jul:73:103143. [Abstract]

    Customer Validation
     Results of incubation with the JC-1 fluorescent probe, FerroOrange probe, DCFH-DA, MitoSOX Red (5 μM; 30 min).

  • 1/16

    MitoSOX Red purchased from MedChemExpress. Usage Cited in: J Nanobiotechnology. 2024 Mar 25;22(1):129. [Abstract]

    Customer Validation
     MitoSOX Red (10 μM; 30 min). Mitochondrial superoxide levels by MitoSOX Red fluorescent staining with MFI quantification. (G&H) Mitochondrial membrane potential by JC-1 staining with calculation of the ratio of red MFI (aggregated JC-1) to green MFI (monomer JC-1).

  • 1/16

    MitoSOX Red purchased from MedChemExpress. Usage Cited in: Chem Eng J. 2024 Oct 15.

    Customer Validation
     MitoSOX Red (5 µM). Mitochondrial ROS in H2O2-stimulated fibroblasts incubated with different hydrogels, assessed by DCFH-DA and MitoSOX staining, respectively.

  • 1/16

    MitoSOX Red purchased from MedChemExpress. Usage Cited in: Small. 2024 Sep;20(37):e2309891. [Abstract]

    Customer Validation
     CLSM images of changes in ROS in mitochondria of HOS cells treated with different groups.

  • 1/16

    MitoSOX Red purchased from MedChemExpress. Usage Cited in: Adv Healthc Mater. 2024 Dec;13(30):e2401909. [Abstract]

    Customer Validation
     MitoSOX Red (5 μM; 30 min). Mitochondrial ROS detected by Mito-SOX RED in control and MCT-PASMCs with or without MPP nanoparticles. Scale bar: 100 µm.

  • 1/16

    MitoSOX Red purchased from MedChemExpress. Usage Cited in: Biomaterials. 2023 Nov:302:122295. [Abstract]

    Customer Validation
     Representative fluorescent images of MitoSOX Red (30 min) in 4T1and LLC cells.

  • 1/16

    MitoSOX Red purchased from MedChemExpress. Usage Cited in: J Hazard Mater. 2023 Sep 5:457:131840. [Abstract]

    Customer Validation
     Representative images of MitoSOX Red (100 nM; 2 h)-staining in P0C. elegans after nanoplastic exposure with different surface charges.

  • MitoSOX Red