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Movronersen

(Synonyms: BIIB-101; ION-464)

Movronersen (BIIB-101; ION-464) is an antisense oligonucleotide that targets SNCA; it promotes the degradation of SNCA mRNA and downregulates the synthesis of α-synuclein. By reducing the production of α-synuclein, Movronersen decreases protein misfolding and aggregation, thereby interfering with the pathological progression of synucleinopathies. Movronersen is used in research related to multiple system atrophy and associated disorders.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

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    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Movronersen Chemical Structure
    Movronersen Chemical Structure
CAS. Nr.: 2411937-33-0
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Use of MCE Products

Alle α-synuclein Isoform-spezifische Produkte anzeigen

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Alle DNA/RNA Synthesis Isoform-spezifische Produkte anzeigen

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  • Movronersen Chemical Structure
    Movronersen Chemical Structure DNA, d([2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]rA-sp-T-sp-A-sp-T-sp-T-sp-T-sp-T-sp-T-sp-G-sp-T-sp-T-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]m5rC-sp-[2'-O-(2-methoxyethyl)]m5rC)
    1/16
  • DNA, d([2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-sp-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]rA-sp-T-sp-A-sp-T-sp-T-sp-T-sp-T-sp-T-sp-G-sp-T-sp-T-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]m5rC-sp-[2'-O-(2-methoxyethyl)]m5rC)