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Art. -Nr.: HY-N16067

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Penipanoid C

Penipanoid C (Compound 9) is a BRD4 inhibitor. Penipanoid C can be isolated from marine sediment-derived fungus Penicillium paneum SD-44. Penipanoid C has anti-inflammatory activity and cytotoxic activity against the SMMC-7721 cells. Penipanoid C can be used for inflammatory diseases research.

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CAS. Nr.: 1442381-95-4
Formel: C₁₅H₁₀N₂O₃
Molecular Weight:266.25

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Penipanoid C Chemical Structure

CAS. Nr.: 1442381-95-4

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
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Help & FAQs
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Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

BRD4

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Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	>50 μM Compound: 3a	Cytotoxicity against human HepG2 cells assessed as inhibition of proliferation incubated for 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as inhibition of proliferation incubated for 72 hrs by MTT assay	[PMID: 34237623]

Chemical Information

CAS. Nr. 1442381-95-4
Molecular Weight 266.25
Formel C₁₅H₁₀N₂O₃
SMILES

O=C1N=C(C(C2=CC=C(C=C2)O)=O)NC3=C1C=CC=C3
Structure Classification
- Alkaloids
- Quinoline Alkaloids
Initial Source
- Marine natural products
- Marine microorganism
Penicillium oxalicum
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Chen S, et al. Marine natural product-inspired discovery of novel BRD4 inhibitors with anti-inflammatory activity. Eur J Med Chem. 2025 Feb 15;284:117193. [Content Brief]

[2]. Li CS, et al. Triazole and dihydroimidazole alkaloids from the marine sediment-derived fungus Penicillium paneum SD-44. J Nat Prod. 2011 May 27;74(5):1331-4. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Penipanoid C

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Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Penipanoid C Related Classifications

HY-N16067 Related Classifications