PF-06745013
PF-06745013 (Compound 37) is a MAP4K4 inhibitor without time-dependent inhibition (TDI) risk of CYP3A4 (IC50 of 0.4 nM for MAP4K4). PF-06745013 has no accumulation CNS-impaired and non-ATP competitive activities in mouse models. PF-06745013 can be used for inflammatory diseases like diabetes and cancers research.
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- CAS. Nr.: 2089334-01-8
- Formel: C21H19ClN2O3
- Molecular Weight:382.84
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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MAP4K4 0.4 nM (IC50) |
Chemical Information
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CAS. Nr. 2089334-01-8
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Molecular Weight 382.84
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Formel C21H19ClN2O3
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SMILES
O=C(C(C)(C)OC1=CC=C(C2=CN=C(C(C3=CC=C(Cl)C=C3)=C2)N)C=C1)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
PF-06745013 Related Classifications
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