Romazarit
Romazarit (RO 31-3948) is an anti-inflammatory agent with antirheumatic effect. Romazarit exhibits PPARα agonist activity. Romazarit (30 mg/kg) inhibits the development of hindpaw inflammation in an adjuvant arthritis model.
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- CAS. Nr.: 109543-76-2
- Formel: C15H16ClNO4
- Molecular Weight:309.74
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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PPARα |
Chemical Information
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CAS. Nr. 109543-76-2
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Molecular Weight 309.74
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Formel C15H16ClNO4
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SMILES
CC(C)(OCC1=C(C)N=C(C2=CC=C(Cl)C=C2)O1)C(O)=O
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Synonyms
RO 31-3948
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Bloxham DP, et al. Biologic properties of romazarit (Ro 31-3948), a potential disease-modifying antirheumatic drug. J Pharmacol Exp Ther. 1990 Mar;252(3):1331-40. [Content Brief]
[2]. Pillai AD, et al. Tetra substituted thiophenes as anti-inflammatory agents: exploitation of analogue-based drug design. Bioorg Med Chem. 2005 Dec 15;13(24):6685-92. [Content Brief]
[3]. Clary Clish, et al. Romazarit for treating metabolic diseases. WO2010014771A1.
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Romazarit Related Classifications
HY-106027 Related Classifications
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