SC-57461
Based on 2 publication(s) in Google Scholar
SC-57461 is a potent, orally active, nonpeptide, and selective inhibitor of Leukotriene A4 (LTA4) hydrolase with IC50s of 2.5 nM, 3 nM, and 23 nM for recombinant human, mouse, and rat LTA4 hydrolase, respectively.
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- CAS. Nr.: 179022-08-3
- Formel: C20H25NO3
- Molecular Weight:327.42
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Publications Citing Use of MedChemExpress (MCE) SC-57461
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
LTA4H hydrolase 2.5 (human nM (Ki) |
LTA4H hydrolase 3 (mouse) nM (Ki) |
LTA4H hydrolase 23 (rat) nM (Ki) |
Chemical Information
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CAS. Nr. 179022-08-3
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Molecular Weight 327.42
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Formel C20H25NO3
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SMILES
O=C(CCN(CCCOC1=CC=C(CC2=CC=CC=C2)C=C1)C)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (2)
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Journal Impact Factor
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Most Recent
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Redox Biol
Endogenous acrolein accumulation in akr7a3 mutants causes microvascular dysfunction due to increased arachidonic acid metabolism. [Abstract]2025 Jun:83:103639. PMID: 40258306 -
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
SC-57461 Related Classifications
HY-10828 Related Classifications
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