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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2438 Results for "
decrease
" in MedChemExpress (MCE) Product Catalog:
Products (2438)
2438 Results for "decrease" in MCE Product Catalog:
Art. -Nr.: HY-110020
CAS. Nr.: 851320-29-1
Target:
Forschungsgebiete:
rel-O-2050 (Compound O-2050) is a neutral cannabinoid CB1 receptor antagonist. rel-O-2050 also decreases food intake in mice .
Art. -Nr.: HY-111308
CAS. Nr.: 847554-50-1
Target:
Forschungsgebiete:
RTI-118 is a novel small-molecule neuropeptide S receptor (NPSR) antagonist. RTI-118 can relieve agent addiction including selectively decrease self-administration .
Art. -Nr.: HY-117805
CAS. Nr.: 177847-28-8
Target:
Forschungsgebiete:
UR-7247 is a potent and orally active angiotensin II AT1 receptor antagonist. UR-7247 decreases arterial pressure and increases renal blood flow .
Art. -Nr.: HY-119926
CAS. Nr.: 15358-48-2
Synonyms: Hydroxylupanine
Target:
Forschungsgebiete:
13-Hydroxylupanine (Hydroxylupanine) is the typical alkaloid profile of sweet lupins.13-Hydroxylupanine blocks ganglionic transmission, decreases cardiac contractility and contracts uterine smooth muscle .
Art. -Nr.: HY-119926A
CAS. Nr.: 6809-89-8
Synonyms: Hydroxylupanine hydrochloride
Target:
Art. -Nr.: HY-126852
CAS. Nr.: 163217-70-7
Synonyms: P-Hydroxyatorvastatin lactone; 4-ATL
Target:
Forschungsgebiete:
4-Hydroxy Atorvastatin lactone is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids .
Art. -Nr.: HY-136676
CAS. Nr.: 122088-76-0
Cgp 38560 methanesulfonate is a well-tolerated renin inhibitor. Cgp 38560 methanesulfonate caused a dose-dependent decrease in angiotensin II and plasma renin activity, and a dose-dependent increase in active renin.
Art. -Nr.: HY-147327
CAS. Nr.: 26367-45-3
Target:
Forschungsgebiete:
N-Formylsarcolysine has antitumor activity, and inhibits leukemia by increasing the Hb and erythrocyte levels and decreasing the number of leukocytes. N-Formylsarcolysine also involves in glioblastoma and other diseases research .
Synonyms: N-Alloc doxorubicin
Forschungsgebiete:
Alloc-DOX (N-Alloc doxorubicin) is a Doxorubicin (HY-15142A) prodrug. The combination of a catalyst (such as nano-palladium) and alloc-DOX leads to a decrease in cell viability and tumour growth .
Art. -Nr.: HY-163279
CAS. Nr.: 885902-66-9
Target:
Forschungsgebiete:
Fluopipamine is an antagonist for Cellulose Synthase 1 (CESA1) with an IC50 of 0.78 μM. Fluopipamine leads a decrease in glucose uptake into cellulose and hyperaccumulation of CESAs at the PM in etiolated Arabidopsis seedlings .
Art. -Nr.: HY-179114
CAS. Nr.: 1211788-57-6
Target:
Forschungsgebiete:
VU0519975 is a raft destabilizing compound. VU0519975 reduces PMP22 raft partitioning and destabilizes ordered domains. VU0519975 significantly decreases the fraction of phase separated GPMVs .
Art. -Nr.: HY-180958
CAS. Nr.: 3104316-26-6
Chlorohexane-PEG-clozapine is a HaloTag PROTAC degrader based on Clozapine (HY-14539). Chlorohexane-PEG-clozapine leads to a significant decrease in the luminescence intensity and protein level of Halo-Eluc .
Art. -Nr.: HY-B0606A
CAS. Nr.: 59985-21-6
Synonyms: INS365 free base
Forschungsgebiete:
Diquafosol (INS365 free base) is a potent P2Y2 agonist. Diquafosol nhibits apoptosis and decreases ROS generation. Diquafosol has the potential for the research of dry eye .
Art. -Nr.: HY-N7646
CAS. Nr.: 143601-09-6
Category:
Plant Other Diseases Amaryllidaceae Extract Phenols Polyphenols Hypoxidaceae Extract Disease Research Fields Curculigo orchioides Gaertn. Extract
Target:
Art. -Nr.: HY-P3637
CAS. Nr.: 2640019-27-6
Target:
Forschungsgebiete:
Art. -Nr.: HY-P99627
CAS. Nr.: 1708936-80-4
Synonyms: NV-02; PG110; ABT-110
Target:
Forschungsgebiete:
Art. -Nr.: HY-116953
CAS. Nr.: 98049-69-5
Synonyms: LXB4
Target:
Forschungsgebiete:
Lipoxin B4 (LXB4) is a structurally distinct product of arachidonic acid metabolism. Lipoxin B4 reduces leukocyte infiltration and mucus secretion in the nasal mucosa and decreases mast cell and eosinophil degranulation in the upper airway. Lipoxin B4 decreases airway inflammation, mucus metaplasia and hyper- responsiveness in the lower airway. Lipoxin B4 shows mucosal protective actions and has the potential for the research of allergic inflammation in the upper and lower airways .
The product specifications provided below refer solely to the active content of Lipoxin B4.
The product specifications provided below refer solely to the active content of Lipoxin B4.
Art. -Nr.: HY-120152
CAS. Nr.: 1449765-82-5
Target:
Forschungsgebiete:
SLP7111228 is a selective sphingosine kinase 1 (SphK1) inhibitor and anti-inflammatory agent. SLP7111228 selectively inhibits SphK1 and reduces the production of sphingosine-1-phosphate. SLP7111228 decreases lipopolysaccharide-induced TNFα and IL-1β levels. SLP7111228 alleviates obliterative pulmonary arteriopathy, increases cardiac index and decreases total pulmonary vascular resistance index. SLP7111228 can be used in research related to neuroinflammatory diseases and pulmonary hypertension .
Target:
Forschungsgebiete:
SLP7111228 hydrochloride is a selective sphingosine kinase 1 (SphK1) inhibitor and anti-inflammatory agent. SLP7111228 hydrochloride selectively inhibits SphK1 and reduces the production of sphingosine-1-phosphate. SLP7111228 hydrochloride decreases lipopolysaccharide-induced TNFα and IL-1β levels. SLP7111228 hydrochloride alleviates obliterative pulmonary arteriopathy, increases cardiac index and decreases total pulmonary vascular resistance index. SLP7111228 hydrochloride can be used in research related to neuroinflammatory diseases and pulmonary hypertension .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
