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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2438 Results for "
decrease
" in MedChemExpress (MCE) Product Catalog:
Products (2438)
2438 Results for "decrease" in MCE Product Catalog:
Art. -Nr.: HY-B0094S
CAS. Nr.: 176652-07-6
Synonyms: Qinghaosu-d3; NSC 369397-d3
Art. -Nr.: HY-B0523B
CAS. Nr.: 823178-43-4
Target:
Forschungsgebiete:
Anagrelide hydrochloride monohydrate is a potent inhibitor of phosphodiesterase type III (PDE3) (IC50=36 nM). Anagrelide hydrochloride monohydrate, an imidazoquinazoline derivative, acts as an inhibitor of platelet aggregation. Anagrelide hydrochloride monohydrate inhibits bone marrow megakaryocytopoiesis. Anagrelide hydrochloride monohydrate decreases gastrointestinal stromal tumor (GIST) cell proliferation and promotes their apoptosis in vitro. Anagrelide hydrochloride monohydrate is a platelet-lowering agent and plays in the antithrombopoietic action .
Art. -Nr.: HY-B0588R
CAS. Nr.: 138890-62-7
Synonyms: AL-4862 (Standard)
Forschungsgebiete:
Brinzolamide (Standard) is the analytical standard of Brinzolamide. This product is intended for research and analytical applications. Brinzolamide (AL-4862) is a selective carbonic anhydrase II inhibitor with anIC50 value of 3.2 nM. Brinzolamide hydrochloride reduces intraocular pressure (IOP) by inhibiting ciliary CA-II and decreasing atrial fluid secretion. Brinzolamide can be used in glaucoma disease research .
Art. -Nr.: HY-B2099S
Synonyms: 1-Butylbiguanide-d9 hydrochloride
Art. -Nr.: HY-N0158R
CAS. Nr.: 16837-52-8
Art. -Nr.: HY-N11772R
CAS. Nr.: 875455-92-8
Category:
Target:
Art. -Nr.: HY-N12042
CAS. Nr.: 110300-77-1
Art. -Nr.: HY-N19627
CAS. Nr.: 607357-35-7
Synonyms: 3′-M-ECG
Category:
Plant Flavonoids Camellia sinensis (L.) O. Ktze. Extract Other Flavonoids Theaceae Extract
Target:
Art. -Nr.: HY-N5097
CAS. Nr.: 29623-29-8
Target:
Target:
Forschungsgebiete:
Art. -Nr.: HY-P11782
CAS. Nr.: 254732-11-1
Art. -Nr.: HY-P1306
CAS. Nr.: 869705-22-6
Target:
Forschungsgebiete:
Art. -Nr.: HY-P99608
CAS. Nr.: 569658-80-6
Art. -Nr.: HY-W017448
CAS. Nr.: 24307-26-4
Synonyms: N,N-Dimethylpiperidinium chloride; PIX
Forschungsgebiete:
Mepiquat chloride (N,N-Dimethylpiperidinium chloride) is a systemic plant growth regulator. Mepiquat chloride reduces the activity of RuBP carboxylase. Mepiquat chloride decreases plant height, total length of vegetative and fruiting branches, and total leaf area of cotton. Mepiquat chloride reduces the net photosynthetic rate of cotton leaves. Mepiquat chloride promotes starch accumulation in cotton leaves without altering sucrose content .
Art. -Nr.: HY-W110242A
CAS. Nr.: 194979-70-9
Target:
Forschungsgebiete:
(S)-CPP sodium serves as an inhibitor of the branched-chain α-ketoacid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, the inhibition of BDK by (S)-CPP (with an IC50 of 6.3 μM) results in the activation of the complex and a notable decrease in plasma levels of leucine/isoleucine and valine in wild-type mice.
Art. -Nr.: HY-W201317
CAS. Nr.: 1060968-92-4
Target:
Forschungsgebiete:
E17241 is an inducer of the expression of ABCA1 that increases the protein levels of ABCA1 in RAW 264.7 macrophages. E17241 is also an agonist of peroxisome proliferator-activated receptors (PPARs ). E17241 decreases plasma glucose levels and body weight in KKAy diabetic mice fed a high-fat and high-glucose (HFHG) diet .
Art. -Nr.: HY-W707564
Art. -Nr.: HY-112726A
CAS. Nr.: 1478364-40-7
Synonyms: BI-1467335 free base
Forschungsgebiete:
PXS-4728A free base is an orally active, selective VAP-1/SSAO inhibitor with an IC50 of 5 nM and a Ki of 175 nM. PXS-4728A free base inhibits the expression of MMP-9. It reduces cell rolling, adhesion and migration, decreases cell infiltration levels, pro-inflammatory cytokines, chemokines and collagen deposition, and improves pulmonary function. PXS-4728A free base reduces the formation and progression of atherosclerotic plaques, and decreases blood lipid and blood glucose levels as well as body weight gain. PXS-4728A free base can be used in research related to chronic obstructive pulmonary disease, cystic fibrosis, acute pulmonary inflammation, acute lung injury, bronchiolitis obliterans syndrome, rhinovirus-exacerbated asthma, sepsis, Klebsiella pneumoniae pulmonary infection and atherosclerosis .
Art. -Nr.: HY-169480
CAS. Nr.: 3003022-09-8
Lipid C2 is an ionizable cationic lipid that has been used in the formation of lipid nanoparticles (LNP) for mRNA delivery in vivo. LNPs containing Lipid C2 and encapsulating an mRNA reporter selectively accumulate in the liver and spleen but not the heart, lungs, or kidneys in mice. LNP containing Lipid C2 and encapsulating mRNA encoding the Epstein-Barr virus (EBV) protein latent membrane protein 2 (LMP-2), in combination with an anti-programmed cell death protein 1 (PD-1) antibody, decrease tumor volume and reverse T cell exhaustion, as well as increase the percentage of CD3 +CD8 + central and CD3 +CD8 + effector memory T cells and decrease the percentage of CD3 + T cells expressing Pd-1, in the spleen in a CT26 murine EBV-infected colon cancer model .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
