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Art. -Nr.: HY-187907

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Surbinsertib

Name: Surbinsertib
Brand: MedChemExpress
SKU: HY-187907
Availability: PreOrder

(Synonyms: SGR-3515)

Surbinsertib (SGR-3515) is an orally active dual inhibitor of the Wee1 and Myt1 kinases. Surbinsertib is used in cancer research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 3038330-83-2
Formel: C₃₀H₄₀N₈O₂S
Molecular Weight:576.76

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Surbinsertib Chemical Structure

CAS. Nr.: 3038330-83-2

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Surbinsertib (SGR-3515) is an orally active dual inhibitor of the Wee1 and Myt1 kinases. Surbinsertib is used in cancer research^[1]^[2].

Alle Wee1 Isoform-spezifische Produkte anzeigen :

PKMYT1

In Vitro

Both Wee1 and Myt1 are CDK-inhibitory kinases. Wee1 primarily phosphorylates CDK1‑Tyr15, while Myt1 phosphorylates both CDK1‑Tyr15 and Thr14. The two kinases act synergistically to inhibit CDK1 activity and regulate the G2/M cell cycle transition.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3038330-83-2
Molecular Weight 576.76
Formel C₃₀H₄₀N₈O₂S
SMILES

C[C@]12[C@](CC(C)(OC2)C)([H])N(C3=CC=CC(N=S(C)(C)=O)=N3)C4=NC(NC5=CC=C(N6CCN(CC6)C)C=C5)=NC=C41
Synonyms

SGR-3515
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. WHO Drug Information, Vol. 40, No. 2, 2026

[2]. Shaoxian Sun, et al, Abstract 3025: Optimization of therapeutic index of SGR-3515, a first-in-class Wee1/Myt1 inhibitor through intermittent dosing for monotherapy and combination with chemotherapy in xenograft tumor models. Cancer Res 15 April 2025; 85.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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