Teloxantrone
Teloxantrone (CI-937; DUP 937) is a DNA synthesis inhibitor (IC50: 0.33 μM). Teloxantrone has antitumor activity and can be used in colorectal cancer research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 91441-48-4
- Formel: C21H25N5O4
- Molecular Weight:411.45
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle DNA/RNA Synthesis Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
1.4 x 10-7M
Compound: 74
|
Tested in vitro against murine L1210 leukemia.
Tested in vitro against murine L1210 leukemia.
|
[PMID: 3806589] |
| L1210 | IC50 |
1.40E-07 M
Compound: 74
|
Tested in vitro against murine L1210 leukemia.
Tested in vitro against murine L1210 leukemia.
|
[PMID: 3806589] |
Chemical Information
-
CAS. Nr. 91441-48-4
-
Molecular Weight 411.45
-
Formel C21H25N5O4
-
SMILES
CNCCNC1=C2C3=C(C=C1)N(CCNCCO)N=C3C4=C(C(O)=CC=C4O)C2=O
-
Synonyms
CI-937; DUP 937
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Fry DW, et al. In vitro DNA strand scission and inhibition of nucleic acid synthesis in L1210 leukemia cells by a new class of DNA complexers, the anthra[1,9-cd]pyrazol-6(2H)-ones (anthrapyrazoles). Biochem Pharmacol. 1985 Oct 1;34(19):3499-508. [Content Brief]
[2]. Maroun JA, et al. Phase II study on DuP 937 (Teloxantrone) in colorectal carcinoma. A Canadian National Cancer Institute Clinical Trial Group study. Invest New Drugs. 1993 May-Aug;11(2-3):235-7. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Teloxantrone Related Classifications
HY-106090 Related Classifications
Powered by Bioz