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Art. -Nr.: HY-15148S2

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Tipranavir-d₅

(Synonyms: PNU-140690-d₅)

Tipranavir-d₅ (PNU-140690-d₅) is the deuterium labeled Tipranavir (HY-15148). Tipranavir (PNU-140690) inhibits the enzymatic activity and dimerization of HIV-1 protease, exerts potent activity against multi-protease inhibitor (PI)-resistant HIV-1 isolates with IC₅₀s of 66-410 nM. Tipranavir inhibits SARS-CoV-2 3CL^pro activity.

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CAS. Nr.: 1126619-17-7
Formel: C₃₁H₂₈D₅F₃N₂O₅S
Molecular Weight:607.70

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tipranavir-d₅ Chemical Structure

CAS. Nr.: 1126619-17-7

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Biologische Aktivität
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Bioz

Biologische Aktivität

Beschreibung

Alle HIV Isoform-spezifische Produkte anzeigen :

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Anwendung

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

CAS. Nr. 1126619-17-7
Unlabeled Cas 174484-41-4
Molecular Weight 607.70
Formel C₃₁H₂₈D₅F₃N₂O₅S
SMILES

O=S(C1=NC=C(C(F)(F)F)C=C1)(NC2=CC=CC([C@H](C3=C(O)C[C@@](CCC)(CCC4=C([2H])C([2H])=C([2H])C([2H])=C4[2H])OC3=O)CC)=C2)=O
Synonyms

PNU-140690-d₅
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.