VU0455691
VU0455691 is a potent, selective orthosteric M1 mAChR antagonist (pIC50=6.64; IC50=0.23 µM for hM1).
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- CAS. Nr.: 1392443-41-2
- Formel: C24H25N5O3S
- Molecular Weight:463.55
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
0.23 μM
Compound: 12a, VU0455691
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Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fluorescence analysis
Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fluorescence analysis
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[PMID: 22749871] |
Chemical Information
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CAS. Nr. 1392443-41-2
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Molecular Weight 463.55
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Formel C24H25N5O3S
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SMILES
O=C(C1CN(C1)S(=O)(C2=CC=CC3=C2C=CN=C3)=O)N4CC5CN(CC5C4)C6=CC=NC=C6
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
VU0455691 Related Classifications
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