VU6005806
VU6005806 (AZN-00016130) is a potent muscarnic acethylcholine receptor subtype 4 (M4) positive allosteric modulator (PAM), with EC50s of 94 nM, 28 nM, 87 nM and 68 nM for human, rat, dog and cyno M4, respectively. Used in the research of neuropsychiatric disorders.
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- CAS. Nr.: 2180914-37-6
- Formel: C17H16F3N7O2S
- Molecular Weight:439.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
IC50: 94 nM (Human M4), 28 nM (Rat M4), 87 nM (Dog M4), 68 nM (Cyno M4)[1]
Chemical Information
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CAS. Nr. 2180914-37-6
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Molecular Weight 439.41
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Formel C17H16F3N7O2S
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SMILES
NC1=C(C(NC2CN(C3=NC=C(C(F)(F)F)C=N3)C2)=O)SC4=NN=C(OC)C(C)=C41
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Synonyms
AZN-00016130
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)